Evidence map›Paper›PMID 42329323›Full record

ArticleOphthalmology and therapy2026

Long-Term Effects of Phacoemulsification with Goniosynechialysis in Angle-Closure Glaucoma: A 2-Year Prospective Cohort Study.

Feng Gao, Jiajian Wang, Xiangmei Kong, Li Wang, Shaohong Qian, Xinghuai Sun, Yuhong Chen

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Article in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Feng GaoDepartment of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.ORCID http://orcid.org/0000-0001-8227-8273
Jiajian WangDepartment of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Xiangmei KongDepartment of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Li WangDepartment of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Shaohong QianDepartment of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Xinghuai SunDepartment of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Yuhong ChenDepartment of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, 83 Fenyang Road, Shanghai, 200031, China. yuhongchen@fudan.edu.cn.ORCID http://orcid.org/0000-0001-6131-7595

Funding

National Key Research and Development Program of China 2020YFA0112700National Natural Science Foundation of China 81800820National Natural Science Foundation of China 82030027National Natural Science Foundation of China 82371056Shanghai Hospital Development Center SHDC2020CR6029Shanghai Hospital Development Center SHDC 2024CRI031Shanghai Hospital Development Center SHDC2025CCS011
6 · The paper itself

Abstract

introductionThe aim of this study was to compare long-term effect of phacoemulsification combined with goniosynechialysis (Phaco-GSL) in patients with acute primary angle-closure glaucoma (APACG) and those with chronic primary angle-closure glaucoma (CPACG), and to evaluate the influencing factors of the surgical prognosis.

methodsIn this prospective cohort study, patients with APACG or CPACG who underwent Phaco-GSL at the glaucoma clinics of Eye and ear, nose, and throat (ENT) Hospital were recruited consecutively from January 2019 to December 2022. Standardized 2-year follow-ups assessed baseline characteristics and surgical outcomes. The cumulative success rates and influencing factors of surgical prognosis were analyzed.

resultsA total of 213 patients were enrolled, including 116 patients (116 eyes) with APACG and 97 patients (97 eyes) with CPACG. The average age was 64.5 ± 7.2 years and 153 (71.8%) patients were women. The complete success rates at 2 years were 72.4% in the acute group and 65.0% in the chronic group (P = 0.04). The qualified success rates at 2 years were 81.9% in the acute group and 81.4% in the chronic group (P = 0.44). Baseline mean deviation, anterior chamber depth (ACD), and glaucoma type were identified as independent predictors of surgical outcomes in the overall cohort. In subgroup analyses, a longer duration of elevated intraocular pressure showed a trend toward poorer surgical prognosis in acute PACG, whereas shallower ACD was associated with poorer outcomes in chronic PACG.

conclusionsPhaco-GSL demonstrated significant benefits for both APACG and CPACG, with more pronounced effects for APACG. Identifying patients with prognostic factors preoperatively provides valuable insights for better assessing the outcomes of GSL surgery in PACG.

Indexed as

Acute primary angle-closure glaucomaChronic primary angle-closure glaucomaInfluencing factorsLong term effectPhacoemulsification combined with goniosynechialysis

Identifiers

PMID42329323
PMCPMC13424025

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