Evidence map›Paper›PMID 42328872›Full record

ArticleJournal of bacteriology2026

Low-affinity DNA-binding promotes cooperative activation of natural transformation in

Allison C Hullinger, Virginia E Callahan, Triana N Dalia, Ankur B Dalia

Abstract read
In one paragraph

Article in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Allison C HullingerDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Virginia E CallahanDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Triana N DaliaDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Ankur B DaliaDepartment of Biology, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0003-2203-1230

Funding

Mechanisms and regulation of horizontal gene transfer by natural transformation in Vibrio choleraeR35GM128674 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Ankur Dalia · 2018 to 2026
$3.8M
NIGMS NIH HHS R35 GM128674NIH HHS R35GM128674
6 · The paper itself

Abstract

DNA-binding transcriptional regulators control gene expression in response to environmental cues. A subset of these proteins, called transmembrane transcriptional regulators (TTRs), directly bind DNA to regulate transcription while remaining anchored in the cytoplasmic membrane. Prior work has shown that in the presence of the polysaccharide chitin, two TTRs, TfoS and ChiS, coordinate to induce the expression of TfoR, a small RNA that is critical for natural transformation in

Indexed as

Bacterial ProteinsDNA, BacterialDNA-Binding ProteinsGene Expression Regulation, BacterialTranscription FactorsTransformation, BacterialVibrio choleraeChitinPromoter Regions, GeneticProtein BindingBacterial ProteinsChitinDNA, BacterialDNA-Binding ProteinsTranscription FactorschitinregulationtranscriptionVibrio

Identifiers

PMID42328872
PMCPMC13316777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.