Evidence map›Paper›PMID 42328850›Full record

ArticlePest management science2026

A viral protein hijacks the plant ethylene signaling to manipulate insect feeding behavior.

Ziyi Li, Simin Liu, Guotao He, Ju Zhou, Gufeng Yuan, Zhibing Fu, Ziyang Jiao, Huihua Tan, Wenwei Tang, Wen Li and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ziyi Li *Guangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Simin Liu *Guangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Guotao HeGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Ju ZhouGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Gufeng YuanGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Zhibing FuGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Ziyang JiaoGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Huihua TanGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Wenwei TangGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.ORCID https://orcid.org/0000-0003-2475-8599
Wen LiGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Yanmei LiuGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Yafei TangPlant Protection Research Institute, Guangdong Academy of Agricultural Sciences, Guangdong Provincial Key Laboratory of High Technology for Plant Protection, Guangzhou, China.
Zifu HePlant Protection Research Institute, Guangdong Academy of Agricultural Sciences, Guangdong Provincial Key Laboratory of High Technology for Plant Protection, Guangzhou, China.
Tong ZhangGuangdong Province Key Laboratory of Microbial Signals and Disease Control, College of Plant Protection, South China Agricultural University, Guangzhou, China.ORCID https://orcid.org/0000-0002-5725-9510
Zhanbiao LiPlant Protection Research Institute, Guangxi Academy of Agricultural Sciences, Nanning, China.
Shunkang ZhouGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.
Yaling ZhaoGuangxi Key Laboratory of Agro-environment and Agric-product Safety, College of Agriculture, Guangxi University, Nanning, China.ORCID https://orcid.org/0000-0003-2036-5632

Funding

Guangxi Zhuang Autonomous Region Young Talent Subsidy Project (Second Batch, 2025)Innovation Project of Guangxi Graduate Education (YCSW2024111)National Key Research and Development Program of China (2024YFD2300503)National Natural Science Foundation of China (32402321, 32060605)Natural Science Foundation of Guangxi Province (2024GXNSFBA010410, 2025GXNSFAA069914)Open Research Project of Guangdong Provincial Key Laboratory of High Technology for Plant Protection (NO.2024-05)Young Elite Scientists Sponsorship Program by GXAST (GXYESS2025034)
6 · The paper itself

Abstract

backgroundInsect-borne viruses represent a major threat to global agriculture and public health. Rice ragged stunt virus (RRSV), a destructive pathogen transmitted by brown planthopper (Nilaparvata lugens Stå), lacks comprehensive understanding of the molecular mechanisms underlying its replication and transmission.

resultsThis study reveals that the RRSV P6 protein serves as a key regulator of vector-borne transmission by sequentially interacting with RTE1-HOMOLOG 2 (OsRTH2) and ETHYLENE-INSENSITIVE3-LIKE 2 (OsEIL2) in the host ethylene signaling pathway. This biphasic strategy manipulates brown planthopper (BPH) behavior, initially promoting viral replication and subsequently facilitating epidemic spread. Furthermore, the ethylene precursor 1-aminocyclopropane-1-carboxylic acid (ACC) significantly impairs BPH fitness, reducing survival and fecundity.

conclusionsOur study elucidates how a plant virus manipulates the host ethylene signaling pathway to promote its own replication and transmission. Moreover, we identify the ethylene biosynthesis precursor ACC as a potential, environmentally friendly control agent against brown planthoppers. © 2026 Society of Chemical Industry.

Indexed as

EthylenesHemipteraOryzaSignal TransductionViral ProteinsAmino Acids, CyclicAnimalsFeeding Behavior1-aminocyclopropane-1-carboxylic acidAmino Acids, CyclicethyleneEthylenesViral ProteinsACCbrown planthopperOsEIL2OsRTH2P6rice ragged stunt virus

Identifiers

PMID42328850
PMCPMC13569285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.