Evidence map›Paper›PMID 42328620›Full record

ArticleInfectious diseases & immunity2025

Detection of plasmid-mediated

Chetana Dahal, Sanjib Adhikari, Ramesh Sharma Regmi, Sanjeep Sapkota, Nabaraj Adhikari, Supriya Sharma, Megha Raj Banjara, Bimal Sharma Chalise, Prakash Ghimire, Komal Raj Rijal

Abstract read
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In one paragraph

Article in Infectious diseases & immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chetana DahalCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.
Sanjib AdhikariCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.
Ramesh Sharma RegmiCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.
Sanjeep SapkotaDepartment of Microbiology, Birendra Multiple Campus, Tribhuvan University, Bharatpur, Chitwan 44200, Nepal.
Nabaraj AdhikariCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.
Supriya SharmaCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.
Megha Raj BanjaraCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.
Bimal Sharma ChaliseSukraraj Tropical Infectious Disease Hospital, Teku, Kathmandu 44600, Nepal.
Prakash GhimireCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.
Komal Raj RijalCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The emergence of antibiotic resistance, particularly plasmid-mediated colistin resistance, poses a critical threat to global public health, given colistin's role as a last-resort antibiotic for treating multidrug-resistant (MDR) bacterial infections. Despite its significance, data on colistin resistance and the prevalence of mobile colistin resistance ( Methods: A hospital-based cross-sectional study was conducted at Sukraraj Tropical Infectious Disease Hospital in Kathmandu from March to August 2022. A total of 1358 clinical specimens were processed using standard microbiological techniques. Antibiotic susceptibility testing followed the Kirby-Bauer disk diffusion method per the 2016 Clinical and Laboratory Standards Institute guidelines. The minimum inhibitory concentration (MIC) for colistin was determined via agar dilution method. Colistin-resistant strains were further investigated for the detection of Results: A total of 86 Conclusions: This study highlights a concerning prevalence of

Indexed as

Colistin resistanceDrug resistance, multiEscherichia coliMobilized colistin resistant (mcr-1 and mcr-2) gene

Identifiers

PMID42328620
PMCPMC13277576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.