Evidence map›Paper›PMID 42328590›Full record

ArticleFrontiers in medicine2026

Case Report: Perifoveal exudative vascular anomalous complex with secondary fundus hemorrhage.

Ziqing Liu, Xiaoyan Zhang, Xiujuan Du, Chunhuan Niu, Fang Sha, Bo Wen, Yane Gao, Ying Wen

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziqing Liu *Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Xiaoyan Zhang *Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Xiujuan DuAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Chunhuan NiuAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Fang ShaAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Bo WenAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Yane Gao *Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Ying Wen *Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Perifoveal exudative vascular anomalous complex (PEVAC) is a rare macular disorder characterized by isolated, circular aneurysmal lesions surrounding the fovea centralis, typically occurring in otherwise healthy patients without retinal inflammation or vascular abnormalities. This study aimed to highlight a rare case of PEVAC with secondary fundus hemorrhage. Case presentation: This study reports the case of a 44-year-old Chinese woman with PEVAC complicated by secondary fundus hemorrhage. The PEVAC diagnosis was confirmed through fundus fluorescein angiography, indocyanine green angiography, optical coherence tomography, and optical coherence tomography angiography. After intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment, the patient experienced marked improvement in visual acuity, reaching 20/20. Conclusion: The case presented in this study underscores that PEVAC may lead to the rupture and hemorrhage of secondary lesions. Gradual improvement in the patient's vision was achieved through intravitreal anti-VEGF injections. This study found that the menstrual cycle in women may influence disease progression. However, the relationship between the menstrual cycle and disease progression remains unclear.

Indexed as

fundus fluorescein angiographyindocyanine green angiographyintravitreal anti-VEGF therapyoptical coherence tomographyoptical coherence tomography angiographyperifoveal exudative vascular anomalous complexPEVACsecondary fundus hemorrhage

Identifiers

PMID42328590
PMCPMC13275338

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