SynthesisFrontiers in medicine2026
Association between blood lipid levels and preeclampsia: a meta-analysis.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Objective: To quantitatively synthesize the association between maternal blood lipid levels and the risk of preeclampsia (PE), and to evaluate its potential clinical utility for risk stratification monitoring. Methods: Relevant literature was retrieved from international databases (PubMed, Web of Science, the Cochrane Library, Embase) and Chinese databases (CNKI, Wanfang, VIP, SinoMed) up to March 2025. After screening, statistical analyses were conducted using RevMan 5.4.1 software. Heterogeneity was assessed using the Results: A total of 822 studies were initially retrieved, and 12 studies met the inclusion criteria. The meta-analysis showed that compared to controls, HDL levels were significantly lower in PE patients (SMD = -0.14, 95% CI: -0.18 to -0.10, Conclusion: Patients with PE exhibit significant alterations in blood lipid levels, which are associated with adverse pregnancy outcomes. These associations persist after adjusting for BMI, although effect sizes are modest. Blood lipid monitoring may serve as a clinical reference in PE management, but causal inference is precluded due to the observational nature of the included studies.
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