ArticleFrontiers in medicine2026
Latent profile analysis of nurses' knowledge, attitude and practice regarding excessive oxygen therapy and influencing factors.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aims to assess the latent profile characteristics of Chinese nurses' knowledge, attitudes, and practices regarding excessive oxygen therapy and explore the influencing factors of different profile types. Methods: From November to December 2025, convenience sampling was used to select nurses from secondary and tertiary general hospitals in Zunyi City, Guizhou Province, as the study participants. A self-designed demographic characteristics questionnaire and the Knowledge, Attitudes and Practice Scale of Healthcare Professionals on Excessive Oxygen Therapy (KAP-HPEOT) were used as survey tools. Latent profile analysis (LPA) was performed on the nurses' KAP regarding excessive oxygen therapy. Univariate analysis of factors influencing different profiles was performed using the chi-square test and ANOVA, and multivariate analysis was conducted using logistic regression. Results: A total of 743 questionnaires were collected, with 687 valid responses, yielding an effective response rate of 92.46%. Latent profile analysis revealed that nurses' knowledge, attitudes, and practices regarding excessive oxygen therapy could be categorized into three profile types: "Low Knowledge-Moderately Attitude-Moderate Practice" (19.65%), "Moderate Knowledge-Moderately Attitude-Moderate Practice" (20.23%), and "High Knowledge-Positive Attitude-High Practice" (60.12%). Logistic regression analysis indicated that age, work experience, professional title, education level, hospital level, participation in oxygen therapy training, and department were significant influencing factors of nurses' KAP regarding excessive oxygen therapy ( Conclusion: This study confirms that nurses' KAP regarding excessive oxygen therapy can be categorized into three profiles, and demographic-related characteristics significantly influence their KAP. The findings provide an important theoretical basis for nursing managers and educators to develop relevant training programs.
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