Evidence map›Paper›PMID 42328461›Full record

ArticleJournal of bone oncology2026

Carbon fiber-reinforced peek versus titanium implants for the surgical treatment of spinal metastases: Evaluation of local disease control and quality of life.

Luigi Falzetti, Cristiana Griffoni, Simona Rosa, Diana Sarmiento Osorio, Silvia Terzi, Chiara Alcherigi, Mariarita Intagliata, Riccardo Ghermandi, Stefano Bandiera, Giovanni Barbanti Brodano and 7 more

Abstract read
In one paragraph

Article in Journal of bone oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Luigi FalzettiComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Cristiana GriffoniComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Simona RosaDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Diana Sarmiento OsorioDepartment of Orthopedic Surgery, Pontificia Universidad Javeriana, Bogotá, Colombia.
Silvia TerziComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Chiara AlcherigiComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Mariarita IntagliataComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Riccardo GhermandiComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Stefano BandieraComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Giovanni Barbanti BrodanoComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Giuseppe TedescoComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Gisberto EvangelistiComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Valerio PipolaComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Stefano PasiniComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Giovanni TosiniComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Chiara CiniComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Alessandro GasbarriniComplex Spinal Surgery Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carbon fiber-reinforced PEEK (CFRP) spinal instrumentation has emerged as a promising alternative in the oncological setting, allowing for superior postoperative imaging and radiotherapy planning.We aimed to evaluate the survival, local disease control and quality of life in a population of patients with spinal metastases surgically treated with CFRP or titanium implants. Methods: We conducted an observational single-center study on a cohort of 160 patients with vertebral metastases surgically treated from August 2018 to October 2022.Demographic, clinical and surgical data, adverse events and patient-reported outcomes (PROMs) were collected. Results: 129 patients were treated with titanium and 31 patients with CFRP instrumentation. The median survival time of the entire population was 24.3 months, with no statistically significant difference between the two groups ( Conclusion: According to our results, CFRP implants did not confer a statistically significant improvement in survival or local disease control compared with titanium implants.

Indexed as

Carbon fiber reinforced- PEEKCharged particle therapyLocal disease controlSpinal metastasesTitanium

Identifiers

PMID42328461
PMCPMC13280136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.