Evidence map›Paper›PMID 42328301›Full record

ArticleFood technology and biotechnology

Ethyl Acetate Extracts of Edible Mushroom Species Enhance β-Lactam Activity Against an MRSA Isolate

James Blee, Peter O'Hara, Thomas Smyth, Owen Kenny

Abstract read
In one paragraph

Article in Food technology and biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James BleeDepartment of Health and Nutritional Science, Atlantic Technological University, Sligo, Ireland.ORCID https://orcid.org/0000-0003-2709-1865
Peter O'HaraDepartment of Health and Nutritional Science, Atlantic Technological University, Sligo, Ireland.ORCID https://orcid.org/0009-0002-9661-1895
Thomas SmythDepartment of Health and Nutritional Science, Atlantic Technological University, Sligo, Ireland.ORCID https://orcid.org/0000-0003-2913-3782
Owen KennyDepartment of Health and Nutritional Science, Atlantic Technological University, Sligo, Ireland.ORCID https://orcid.org/0000-0002-1206-535X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research background: The rapid emergence of antimicrobial resistance (AMR) has led to numerous pathogens developing resistance to available antibiotics. Experimental approach: Antimicrobial activity (minimum inhibitory concentration (MIC)) and antibiotic-modulating activity (fractional inhibitory concentration index (FICI)) were assessed using the broth microdilution method. The cell viability assay was used to assess cell membrane integrity following treatment to offer insight into potential mechanisms of action. Results and conclusions: Both antimicrobial and antibiotic modulatory activity were found only in ethyl acetate extracts. Novelty and scientific contribution: These results indicate the potential use of ethyl acetate extracts from edible mushrooms, specifically

Indexed as

Agaricus bisporusantibiotic modulationantimicrobial resistanceedible mushroomsMRSAβ-lactams

Identifiers

PMID42328301
PMCPMC13282972

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.