ArticleFrontiers in cellular and infection microbiology2026
Clinical characteristics, opportunistic infection spectrum and epidemiological analysis of pediatric AIDS patients in southwest China.
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: This study aimed to exploring the clinical, opportunistic infections, and epidemiological characteristics of hospitalized pediatric HIV/AIDS patients in southwest China. Methods: Retrospectively analyzed the clinical data of 87 hospitalized pediatric HIV/AIDS patients aged ≤14 years at the Public Health Clinical Center of Chengdu from January 2017 to September 2025, employing statistical methods to examine demographic characteristics, clinical indicators, infection spectrum, geographical distribution, and treatment outcomes. Results: The gender ratio of the affected children was 1.02:1, predominantly Han and Yi ethnic groups, concentrated in the minority regions of western Sichuan, with an average age of 8.70 ± 3.91 years. Parents of 48.3% of the children were AIDS patients, 55.2% received antiretroviral therapy (ART), and 70.0% had reduced CD4 Conclusion: Hospitalized pediatric HIV/AIDS patients in southwestern China is mainly transmitted from mother to child, with severe immune suppression at the time of diagnosis. The distribution of cases is related to medical resources. Although mother to child blockade and ART improve prognosis, there are still shortcomings in prevention and control in remote ethnic areas, and targeted screening, intervention, and medical resource allocation need to be strengthened.
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