Evidence map›Paper›PMID 42328152›Full record

ArticleRespirology case reports2026

Intestinal Ischaemia and Perforation After Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) for Acute Exacerbation of Interstitial Lung Disease: An Autopsy Case.

Hiroka Miyagawa, Shigeo Hanada, Yasuro Miura, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Takahiro Mitsumura, Atsushi Miyamoto, Meiyo Tamaoka

Abstract read
In one paragraph

Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hiroka MiyagawaDepartment Of Respiratory Medicine, Respiratory Center Toranomon Hospital Tokyo Japan.
Shigeo HanadaDepartment Of Respiratory Medicine, Respiratory Center Toranomon Hospital Tokyo Japan.
Yasuro MiuraDepartment Of Pathology Toranomon Hospital Tokyo Japan.
Hiroshi NakahamaDepartment Of Respiratory Medicine, Respiratory Center Toranomon Hospital Tokyo Japan.
Yui TakahashiDepartment Of Respiratory Medicine, Respiratory Center Toranomon Hospital Tokyo Japan.
Yuichiro NeiDepartment Of Respiratory Medicine, Respiratory Center Toranomon Hospital Tokyo Japan.
Takahiro MitsumuraDepartment Of Respiratory Medicine, Respiratory Center Toranomon Hospital Tokyo Japan.
Atsushi MiyamotoDepartment Of Respiratory Medicine, Respiratory Center Toranomon Hospital Tokyo Japan.
Meiyo TamaokaDepartment Of Respiratory Medicine, Respiratory Center Toranomon Hospital Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 75-year-old man with interstitial lung disease was admitted with an acute exacerbation and severe hypoxemic respiratory failure. During intensive care management, he developed acute myocardial infarction, required veno-venous extracorporeal membrane oxygenation and later underwent continuous haemodiafiltration for an acute kidney injury. A pulmonary embolism, gastrointestinal bleeding and intestinal perforation subsequently occurred, and the patient died of septic shock on day 40 of hospitalisation. An autopsy showed diffuse alveolar damage superimposed on a usual interstitial pneumonia pattern, intra-alveolar haemorrhage, a subacute myocardial infarction, pulmonary arterial thrombi, a terminal ileal perforation with transmural necrosis and microthrombi in the intestinal wall. This case illustrates the difficulty of balancing thrombosis and bleeding during and after extracorporeal support for an acute exacerbation of interstitial lung disease and highlights the need for early suspicion of intestinal ischaemia in patients receiving extracorporeal membrane oxygenation who exhibit unexplained anaemia, gastrointestinal bleeding, worsening sepsis, or rising lactate levels, particularly during deep sedation.

Indexed as

acute exacerbationinterstitial lung diseaseintestinal perforationpulmonary embolismveno‐venous extracorporeal membrane oxygenation

Identifiers

PMID42328152
PMCPMC13280554

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.