Evidence map›Paper›PMID 42328047›Full record

ArticleClinical case reports2026

Primary CNS Lymphoma Presenting With Seizures in a Virologically Suppressed HIV Patient With Near-Normal CD4: A Case Report From Uganda.

Abdisalam Ahmed Sandeyl, Abdisamad Guled Hersi, David Elia Saria, Farah Dubad Abdi, Venance Emmanuel Mswelo, Sura Daniel Elias, Elias Amare Hailu, Hailemariam Kassahun Bekele

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Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdisalam Ahmed SandeylInternal Medicine Department Kampala International University, Western Campus Ishaka Uganda.ORCID https://orcid.org/0009-0003-7328-3195
Abdisamad Guled HersiInternal Medicine Department Kampala International University, Western Campus Ishaka Uganda.
David Elia SariaInternal Medicine Department Kampala International University, Western Campus Ishaka Uganda.
Farah Dubad AbdiInternal Medicine Department Kampala International University, Western Campus Ishaka Uganda.
Venance Emmanuel MsweloInternal Medicine Department Kampala International University, Western Campus Ishaka Uganda.
Sura Daniel EliasNeurosurgery Department Kampala International University, Western Campus Ishaka Uganda.
Elias Amare HailuOncology Department Kampala International University, Western Campus Ishaka Uganda.
Hailemariam Kassahun BekeleInternal Medicine Department Kampala International University, Western Campus Ishaka Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of primary central nervous system lymphoma (PCNSL) in a 40-year-old man with well-controlled HIV infection, virologic suppression, and a near-normal CD4 count who presented with new-onset generalized seizures and left lower motor neuron facial palsy. Brain MRI showed a large left temporal lobe lesion with irregular ring enhancement, marked vasogenic edema and mild midline shift. Lumbar puncture was deferred due to mass effect. The patient was stabilized with anticonvulsants and supportive care and transferred for stereotactic biopsy and oncologic management. Stereotactic brain biopsy confirmed PCNSL, and the patient was initiated on high-dose methotrexate-based chemotherapy with adjunctive dexamethasone. This case highlights that PCNSL can occur despite immunologic preservation in HIV and may present acutely with seizures. Early contrast-enhanced MRI, careful timing of corticosteroid use relative to biopsy, and timely referral are essential, particularly in resource-limited settings.

Indexed as

antiretroviral therapyfacial palsyHIV infectionsmagnetic resonance imagingprimary central nervous system lymphomaseizures

Identifiers

PMID42328047
PMCPMC13277294

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.