Evidence map›Paper›PMID 42327924›Full record

ArticleThe International journal of robotics research2015

Tissue removal inside the beating heart using a robotically delivered metal MEMS tool.

Nikolay V Vasilyev, Andrew H Gosline, Arun Veeramani, Ming Ting Wu, Gregory P Schmitz, Richard T Chen, Veaceslav Arabagi, Pedro J Del Nido, Pierre E Dupont

Abstract read
In one paragraph

Article in The International journal of robotics research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Continuum Robots for Medical Interventions.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2022
    Article
  4. Modeling Tube Clearance and Bounding the Effect of Friction in Concentric Tube Robot Kinematics.IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nikolay V VasilyevCardiovascular Surgery, Boston Children's Hospital, Harvard Medical School, USA.
Andrew H GoslineCardiovascular Surgery, Boston Children's Hospital, Harvard Medical School, USA.
Arun VeeramaniMicrofabrica Inc., Van Nuys, CA, USA.
Ming Ting WuMicrofabrica Inc., Van Nuys, CA, USA.
Gregory P SchmitzMicrofabrica Inc., Van Nuys, CA, USA.
Richard T ChenMicrofabrica Inc., Van Nuys, CA, USA.
Veaceslav ArabagiCardiovascular Surgery, Boston Children's Hospital, Harvard Medical School, USA.
Pedro J Del NidoCardiovascular Surgery, Boston Children's Hospital, Harvard Medical School, USA.
Pierre E DupontCardiovascular Surgery, Boston Children's Hospital, Harvard Medical School, USA.

Funding

Image-guided Intracardiac Beating Heart SurgeryR01HL073647 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI DEL NIDO, PEDRO J. · 2003 to 2012
$8.1M
Steerable MEMS Instruments for Precise Intracardiac SurgeryR01HL087797 · NHLBI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI DUPONT, PIERRE E · 2007 to 2011
$5.1M
NHLBI NIH HHS R01 HL073647NHLBI NIH HHS R01 HL087797
6 · The paper itself

Abstract

A novel robotic tool is proposed to enable the surgical removal of tissue from inside the beating heart. The tool is manufactured using a unique metal MEMS process that provides the means to fabricate fully assembled devices that incorporate micron-scale features in a millimeter scale tool. The tool is integrated with a steerable curved concentric tube robot that can enter the heart percutaneously through peripheral vessels. Incorporating both irrigation and aspiration, the tissue removal system is capable of extracting substantial amounts of tissue under teleoperated control by first morselizing it and then transporting the debris out of the heart through the lumen of the robot. Tool design and robotic integration are described, and ex vivo and in vivo large animal experimental results are presented.

Indexed as

heart surgeryMEMS processRobotic tooltissue removal

Identifiers

PMID42327924
PMCPMC13278507

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.