Evidence map›Paper›PMID 42327867›Full record

ArticleJournal of medical cases2026

Transient Supplement-Associated Thyrotoxicosis Without Persistent Hyperthyroidism: A Diagnostic Challenge in Endocrine Practice.

Pavel Stanchev, Ekaterina Babadzhanova, Boris Tilov, Maria Kraeva, Delyana Davcheva

Abstract readCase Reports
In one paragraph

Article in Journal of medical cases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pavel StanchevDepartment and Clinic of Endocrinology and Metabolic Diseases, St. George University Hospital, Medical University of Plovdiv, Plovdiv, Bulgaria.
Ekaterina BabadzhanovaDepartment and Clinic of Endocrinology and Metabolic Diseases, St. George University Hospital, Medical University of Plovdiv, Plovdiv, Bulgaria.
Boris TilovMedical College, Medical University of Plovdiv, Plovdiv, Bulgaria.
Maria KraevaDepartment of Otorhinolaryngology, Medical Faculty, Medical University of Plovdiv, Plovdiv, Bulgaria.
Delyana DavchevaDepartment of Clinical Laboratory, Medical Faculty, Medical University of Plovdiv, Plovdiv, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyrotoxicosis refers to the clinical state resulting from elevated thyroid hormone levels and may occur with or without underlying hyperthyroidism. Recognizing non-thyroidal and iatrogenic causes is essential for accurate diagnosis and management. A 50-year-old woman presented to a cardiologist due to complaints of palpitations. Electrocardiogram and echocardiogram were performed showing sinus tachycardia. Beta-blocker therapy was prescribed with recommendations for thyroid function testing. The laboratory tests performed in a specialized endocrine clinic confirmed transient thyrotoxicosis without hyperthyroidism and a normal ultrasound image of the thyroid gland. Upon further assessment, an iatrogenic cause was suspected as the most plausible contributing factor-the use of a nutritional supplement for menopausal symptoms containing iodine and other active substances. We present a clinical case of transient most likely supplement-associated thyrotoxicosis without persistent hyperthyroidism with subsequent normalization of thyroid function after symptomatic therapy. Exogenous iodine intake in the form of a dietary supplement is discussed as a possible trigger. The article provides information about the diagnostic and therapeutic algorithm in patients with thyrotoxicosis in the light of real clinical practice and emphasizes the importance of detailed medication and supplement history.

Indexed as

HyperthyroidismIodineThyrotoxicosis

Identifiers

PMID42327867
PMCPMC13278701

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.