Evidence map›Paper›PMID 42327856›Full record

ArticleSurgical case reports2026

Repair of Ventricular Septal Defect in Children with

Shinya Ugaki, Shota Ogura, Kazuma Tsuno, Toshikazu Shimizu, Shio Masuda, Ryo Mafune, Kodai Momoki, Sadataka Kawachi, Izumi Hamaya, Kenji Hoshino and 1 more

Abstract readCase Reports
In one paragraph

Article in Surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shinya UgakiDepartment of Cardiovascular Surgery, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Shota OguraDepartment of Cardiovascular Surgery, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Kazuma TsunoDepartment of Cardiology, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Toshikazu ShimizuDepartment of Cardiovascular Surgery, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Shio MasudaDepartment of Cardiology, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Ryo MafuneDepartment of Cardiology, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Kodai MomokiDepartment of Cardiology, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Sadataka KawachiDepartment of Cardiology, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Izumi HamayaDepartment of Cardiovascular Surgery, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Kenji HoshinoDepartment of Cardiology, Saitama Children's Medical Center, Saitama, Saitama, Japan.
Koji NomuraDepartment of Cardiovascular Surgery, Saitama Children's Medical Center, Saitama, Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCASE PRESENTATION: Patient 1, a 7-month-old boy with Klinefelter syndrome and a TAB2 variant, presented with a VSD and extracardiac features. He developed severe congestive heart failure and pulmonary hypertension with impaired biventricular function. Despite medical management, his condition worsened, necessitating surgical patch closure. Postoperatively, he required intensive support, including nitric oxide and inotropes, for low cardiac output and persistent pulmonary hypertension. He was successfully extubated on day 7. Two years after surgery, the patient remains in New York Heart Association (NYHA) functional class I with improved biventricular function. Patient 2, a 1-year-4-month-old boy with a TAB2 gene deletion (6q24.3-q25.1), presented with a VSD, cardiomyopathy, and dysmorphic features. Due to decreased biventricular function, treatment with carvedilol and enalapril maleate was initiated at 3 months of age and his cardiac function gradually improved by 1 year of age. Although surgical patch closure of the VSD was performed, postoperative biventricular failure necessitated a 7-day course of extracorporeal membrane oxygenation. His recovery was further complicated by

conclusionsSuccessful VSD repair was achieved in 2 children with dilated ventricles and impaired cardiac function associated with

Indexed as

cardiomyopathychildrenTAB2ventricular septal defect

Identifiers

PMID42327856
PMCPMC13278802

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.