Evidence map›Paper›PMID 42327782›Full record

ArticleFrontiers in immunology2026

Characterizing the impact of intracutaneous dissemination on host responses during

Samantha Crane, Amira-Nuriya McKinney, Clayton Jarrett, Chad S Clancy, Olof Rickard Nilsson, Kelly L Hawley, Ashley M Groshong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samantha CraneLaboratory of Bacteriology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
Amira-Nuriya McKinneyLaboratory of Bacteriology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
Clayton JarrettLaboratory of Bacteriology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
Chad S ClancyRocky Mountain Veterinary Branch, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
Olof Rickard NilssonLaboratory of Bacteriology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.
Kelly L HawleyDepartments of Pediatrics, Medicine, and Immunology, University of Connecticut School of Medicine, Farmington, CT, United States.
Ashley M GroshongLaboratory of Bacteriology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the unique dissemination phenotype of a mutant in OppA2 of

methodsWe utilized longitudinal infection models to evaluate dissemination, cytometric and histopathologic analysis, spatial immune profiling, ELISA, and host immune response transcriptomics.

resultsDissemination studies demonstrate that at 4 weeks post-inoculation (wpi), in addition to skin colonization,

conclusionsColonization of lymph nodes at 4 week post-inoculation by the

Indexed as

Borrelia burgdorferiHost-Pathogen InteractionsLyme DiseaseSkinAnimalsAntibodies, BacterialBacterial ProteinsDisease Models, AnimalFemaleLymph NodesMiceMice, Inbred C57BLMice, KnockoutMyeloid Differentiation Factor 88Antibodies, BacterialBacterial ProteinsMyeloid Differentiation Factor 88Borrelia burgdorferidisseminationhost responsehumoral responselyme disease

Identifiers

PMID42327782
PMCPMC13278888

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.