Evidence map›Paper›PMID 42327729›Full record

ArticleFrontiers in immunology2026

Rapid phagosome formation drives parasite control in subclinical

Caic Figueiredo, Alan Rocha Dos Santos, Camila Pimentel, Maurício T Nascimento, Fabio Peixoto, Vítor Oliveira, Olivia Bacellar, Lucas P Carvalho, Edgar M Carvalho, Thiago M Cardoso

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Caic FigueiredoLaboratory of Clinical Research (LAPEC), Gonçalo Moniz Institute (IGM), Fiocruz, Salvador, Brazil.
Alan Rocha Dos SantosLaboratory of Clinical Research (LAPEC), Gonçalo Moniz Institute (IGM), Fiocruz, Salvador, Brazil.
Camila PimentelLaboratory of Clinical Research (LAPEC), Gonçalo Moniz Institute (IGM), Fiocruz, Salvador, Brazil.
Maurício T NascimentoLaboratory of Clinical Research (LAPEC), Gonçalo Moniz Institute (IGM), Fiocruz, Salvador, Brazil.
Fabio PeixotoLaboratory of Clinical Research (LAPEC), Gonçalo Moniz Institute (IGM), Fiocruz, Salvador, Brazil.
Vítor OliveiraImmunology Service, Complexo Hospitalar Universitário Prof. Edgard Santos, Federal University of Bahia, Salvador, Brazil.
Olivia BacellarImmunology Service, Complexo Hospitalar Universitário Prof. Edgard Santos, Federal University of Bahia, Salvador, Brazil.
Lucas P CarvalhoLaboratory of Clinical Research (LAPEC), Gonçalo Moniz Institute (IGM), Fiocruz, Salvador, Brazil.
Edgar M CarvalhoLaboratory of Clinical Research (LAPEC), Gonçalo Moniz Institute (IGM), Fiocruz, Salvador, Brazil.
Thiago M CardosoLaboratory of Clinical Research (LAPEC), Gonçalo Moniz Institute (IGM), Fiocruz, Salvador, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cutaneous leishmaniasis (CL) caused by Objective: This study proposed experiments to elucidate the involvement of phagosome formation in the control of intracellular parasites in macrophages (MØ) from SC individuals. The hypothesis of the study is that SC MØ present more quickly and effectively phagosome formation against intracellular parasites compared to CL MØ. Methodology: Monocyte-derived MØ were infected using calcein-labeled Results: Conclusion: SC MØ can form phagosomes more quickly and for longer periods, providing effective parasite control, compared to CL MØ.

Indexed as

Leishmania braziliensisLeishmaniasis, CutaneousMacrophagesPhagosomesAntigens, ProtozoanHumansInterferon-gammaLysosomal-Associated Membrane Protein 1Antigens, ProtozoanInterferon-gammaLysosomal-Associated Membrane Protein 1American tegumentary leishmaniasisleishmania killingphagosome formationpromastigotessubclinical infection

Identifiers

PMID42327729
PMCPMC13278920

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.