ArticleNeuroimage. Reports2026
Lower resting-state functional connectivity between frontoparietal and sensory networks is associated with recent pain intensity in a community sample of youth.
Article in Neuroimage. Reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Self-reported pain symptoms are highly prevalent during adolescence and are associated with significant individual and societal burden; yet their neurobiological correlates remain insufficiently characterized, particularly in large, community-based cohorts. Identifying patterns in resting-state functional connectivity associated with adolescent pain characteristics may elucidate neural factors relevant to future pain and related health risks. The present cross-sectional study utilized linear mixed-effects models to examine associations between resting-state functional connectivity and past-month pain characteristics (average and worst pain intensity, pain-related limitations, daily pain duration, and number of pain body regions) in youth from Year 2 of the Adolescent Brain Cognitive Development Study (ABCD). No significant differences in connectivity were observed between youth with (n = 2,364, 47.7% female, average age = 12.04) or without (n = 4,447, 46.4% female, average age = 11.99) past-month pain. However, among youth reporting pain, higher
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