Evidence map›Paper›PMID 42327539›Full record

ArticleNature. Mental health2025

Machine learning for identifying caregiving adversities associated with greatest risk for mental health problems in children.

Anna Vannucci, Andrea Fields, Charlotte Heleniak, Paul A Bloom, Chelsea Harmon, Aki Nikolaidis, Ian J Douglas, Lisa Gibson, Nicolas L Camacho, Tricia Choy and 5 more

Abstract read
In one paragraph

Article in Nature. Mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Measuring early experiences: Challenges and future directions.Developmental cognitive neuroscience · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Anna VannucciColumbia University, Department of Psychology, Schermerhorn Hall, New York, NY, USA.ORCID 0000-0003-1617-7006
Andrea FieldsColumbia University, Department of Psychology, Schermerhorn Hall, New York, NY, USA.
Charlotte HeleniakColumbia University, Department of Psychology, Schermerhorn Hall, New York, NY, USA.
Paul A BloomColumbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0003-3970-5721
Chelsea HarmonWestern Washington University, Department of Psychology, Bellingham, WA, USA.
Aki NikolaidisChild Mind Institute, New York, NY, USA.
Ian J DouglasColumbia University, Department of Psychology, Schermerhorn Hall, New York, NY, USA.
Lisa GibsonIcahn School of Medicine at Mt. Sinai, New York, NY, USA.
Nicolas L CamachoDuke University, Durham, NC, USA.
Tricia ChoyUniversity of California, Riverside, CA, USA.
Syntia S HadisTeachers College, Columbia University, New York, NY, USA.
Michelle VanTieghemGenesis Research, Hoboken, NJ, USA.
Mary DozierUniversity of Delaware, Department of Psychological and Brain Sciences, Newark, DE, USA.
Michael P MilhamChild Mind Institute, New York, NY, USA.
Nim TottenhamColumbia University, Department of Psychology, Schermerhorn Hall, New York, NY, USA.

Funding

Predicting Heterogeneous Neurodevelopmental Outcomes in School-age Children with Early Caregiving AdversitiesR01MH091864 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MILHAM, MICHAEL PETER, TOTTENHAM, NIM · 2010 to 2022
$5.1M
Neurocomputational Mechanisms of Affective Semantic Memory DevelopmentF99NS134207 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI VANNUCCI, ANNA · 2023 to 2024
$98k
NIMH NIH HHS R01 MH091864NINDS NIH HHS F99 NS134207
6 · The paper itself

Abstract

Developmental and experiential heterogeneity associated with caregiving-related early adversities (crEAs) poses a major challenge to identifying replicable, generalizable findings. Here conditional random forests evaluated the importance of unique crEA experiences for estimating risks to mental health in 306 children, 6-12 years of age, with heterogeneous crEA experiences (different forms of caregiver-involved abuse and/or neglect or permanent/substantial parent-child separation). The better that crEAs improved the accuracy of symptom estimates in held-out, never-before-seen children, the more important and generalizable they were considered. Here we show that earlier timing and longer duration of crEAs was especially important for elevated general psychopathology (

Identifiers

PMID42327539
PMCPMC13277297

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.