ArticleRadiology case reports2026
Primary hepatic angiosarcoma misdiagnosed as hemangioma despite repeated negative biopsies and sclerotherapy: A diagnostic pitfall.
Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Primary hepatic angiosarcoma is a very rare vascular malignancy with highly variable imaging and pathologic appearances, occasionally resembling a benign hemangioma. We describe a 62-year-old woman who presented with profound anemia and severe thrombocytopenia and multifocal hepatic lesions repeatedly interpreted as hemangioma on core needle biopsies. She underwent 1 sessions of sclerotherapy. With rapid interval enlargement and atypical MRI features, a repeat biopsy established the diagnosis of hepatic angiosarcoma, supported by immunohistochemistry. Her course was complicated by acute kidney injury requiring hemodialysis; she subsequently suffered 2 cardiac arrests 1 day apart and finally died despite resuscitation. This case underscores the need to revisit the diagnosis when a presumed hemangioma shows progressive growth, atypical enhancement patterns, or discordant clinical behavior.
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