Evidence map›Paper›PMID 42327502›Full record

ArticleArchives animal breeding2025

miR-383 regulates sheep granular cell proliferation and apoptosis by targeting

Binglei Zhang, Saiyi Sun, Wanhang Jia, Jiaxin Yang, Xueru Dou, Yang Wang, Yuqin Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives animal breeding, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Binglei ZhangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, China.ORCID https://orcid.org/0000-0002-2764-0126
Saiyi SunCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, China.
Wanhang JiaCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, China.
Jiaxin YangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, China.
Xueru DouCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, China.
Yang WangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, China.
Yuqin WangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the reproductive process in female mammals, approximately 99 % of the follicles involved in egg development undergo atresia and are not utilised. The primary cause of follicular atresia is granulosa cell (GC) apoptosis. MicroRNAs (miRNAs) play an important regulatory role in follicular atresia. It has been widely confirmed that miR-383 is involved in the regulation of follicular GC proliferation, apoptosis, and steroid hormone secretion; however, its regulatory effect on sheep ovarian follicles remains unknown. In this study, we examined the regulatory role of miR-383 in ovine ovarian GC proliferation and apoptosis. We reveal that miR-383 overexpression induces cell death, inhibits cell proliferation, and causes a G1-phase cell cycle arrest. Based on prediction analysis of its target genes, miR-383 potentially targets the anti-apoptotic gene,

Identifiers

PMID42327502
PMCPMC13282089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.