Evidence map›Paper›PMID 42327495›Full record

ArticleBioactive materials2026

Sirt1 transgene delivery improves diabetes-impaired wound healing.

Ruyue Luo, Huifeng Wang, Chongwen Duan, Michelle Jen, Hsin-Yu Kuo, Xinlong Wang, Milan Mrksich, Guillermo Ameer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruyue LuoInstitute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, Sichuan, 637100, China.
Huifeng WangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Chongwen DuanDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Michelle JenDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Hsin-Yu KuoDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Xinlong WangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Milan MrksichDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Guillermo AmeerDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus severely impairs wound healing, in part due to persistent inflammation, impaired angiogenesis, and dysregulated cellular responses. Sirtuin-1 (Sirt1), an NAD

Indexed as

Diabetic wound healingInflammation modulationSirt1Therapeutic gene delivery

Identifiers

PMID42327495
PMCPMC13277535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.