Evidence map›Paper›PMID 42327428›Full record

ArticleCJC open2026

Sex Differences in the Effects of High Temperature on Cardiovascular Disease Hospitalizations in Montreal.

Yusheng Zhou, Sasha Ramkhelawan, Bulemba Katende, Hassan Behlouli, Louise Pilote

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Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yusheng ZhouResearch Institute of McGill University Health Centre, McGill University, Montreal, Quebec, Canada.
Sasha RamkhelawanDepartment of Physics, Faculty of Science and Technology, The University of the West Indies, St. Augustine Campus, Trinidad and Tobago.
Bulemba KatendeResearch Institute of McGill University Health Centre, McGill University, Montreal, Quebec, Canada.
Hassan BehlouliResearch Institute of McGill University Health Centre, McGill University, Montreal, Quebec, Canada.
Louise PiloteResearch Institute of McGill University Health Centre, McGill University, Montreal, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Climate change has increased temperatures in Canada. Although heat-related mortality is well documented, less is known about its impact on cardiovascular disease (CVD) morbidity, particularly hospitalization patterns. This study examines the association between ambient temperature and CVD hospitalizations in Montreal, focusing on sex-stratified vulnerability. Methods: A time-series analysis was conducted in Montreal, Quebec, examining CVD hospitalizations during the warm season (May 1-September 30) from 2018-2022. Ambient temperature was represented by daily mean temperature. Analyses were stratified by sex and heat vulnerability index (HVI) levels. The HVI integrates multiple vulnerability dimensions (exposure index, sensitivity index, and coping capacity index); higher HVI scores indicate greater vulnerability to extreme heat impacts. Daily mean temperature (lag, 0-7 days) and CVD hospitalizations were analyzed using distributed lag nonlinear models, adjusting for possible confounders. Results: Among 262,740 CVD patient hospitalizations (mean age 76.4 years; 49.6% female), the relative risk (RR) for CVD hospitalization at the 99th percentile of temperature (28.1°C), as compared to the identified minimum morbidity temperature (MMT; 23°C) for the total population was 1.08 (95% confidence interval [CI]: 1.05-1.11). Although overall heat-related risk was similar between sexes, vulnerability components revealed differences. Female participants exhibited significant cardiovascular risk in areas with poor adaptive resources based on coping capacity index (RR = 1.13, 95% CI: 1.04-1.23), whereas male patients did not (RR = 1.03, 95% CI: 0.96-1.12), suggesting greater susceptibility when community-level resources are limited. Conclusions: Female participants demonstrated greater vulnerability in areas lacking adaptive resources, indicating that sex-specific heat-protection strategies should prioritize enhancement of community-level cooling infrastructure and support systems.

Indexed as

cardiovascular diseaseclimate changeheat exposureheat vulnerability indexsex differences

Identifiers

PMID42327428
PMCPMC13282528

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.