Evidence map›Paper›PMID 42327427›Full record

ArticleNPJ dementia2026

Functional network contributions to longitudinal tau spread in Posterior Cortical Atrophy.

Yuta Katsumi, Ryan Eckbo, Scott M McGinnis, Jorge Sepulcre, Gil D Rabinovici, Renaud La Joie, Bradford C Dickerson, Deepti Putcha

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ dementia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuta KatsumiFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA.
Ryan EckboFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA.
Scott M McGinnisFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA.
Jorge SepulcreDepartment of Radiology and Biomedical Imaging, Yale PET Center, Yale Biomedical Imaging Institute, Yale School of Medicine, Yale University, New Haven, CT USA.
Gil D RabinoviciMemory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA USA.
Renaud La JoieMemory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA USA.
Bradford C DickersonFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA.
Deepti PutchaFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA.

Funding

Neurogenetic contributions to the spread of tau pathology in sporadic early-onset Alzheimer's diseaseK01AG084820 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Yuta Katsumi · 2024 to 2026
$387k
NIA NIH HHS K01 AG084820
6 · The paper itself

Abstract

In this study, we investigated longitudinal tau spreading in 23 amyloid-positive individuals with early-stage posterior cortical atrophy (PCA), a clinical syndrome typically characterized by progressive visual cognitive deficits emerging largely from underlying Alzheimer's disease-related tau deposition in posterior cortical areas. Each PCA participant underwent structural MRI and

Indexed as

DiseasesNeurologyNeuroscience

Identifiers

PMID42327427
PMCPMC13282171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.