ArticleInternational journal of endocrinology2026
Association Between Thyroid Function Indicators and Metabolic-Associated Fatty Liver Disease: Effect Modification by Iodine Nutritional Status.
Article in International journal of endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Association Between Thyroid Function Indicators and Metabolic-Associated Fatty Liver Disease: Effect Modification by Iodine Nutritional Status.International journal of endocrinology · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The relationship between thyroid function indicators and metabolic dysfunction-associated fatty liver disease (MAFLD) has yielded contradictory results. This study aimed to explore the association between thyroid function indicators and MAFLD, as well as the modifying effect of iodine nutritional status. Methods: This cross-sectional analysis utilized nationally representative data from the 2009-2012 National Health and Nutrition Examination Survey (NHANES). Different multivariate logistic regression models were constructed to investigate the association between thyroid function indicators and MAFLD. Mediation analyses were performed to explore the mediating roles of MAFLD diagnosis-related variables. Lastly, we analyzed the relationship between thyroid function indicators and MAFLD across different iodine nutritional statuses. Results: After adjusting for covariates unrelated to MAFLD diagnosis, elevated FT3 and FT3/FT4 and decreased FT4 levels increased the odds of MAFLD across three adjusted models (all Conclusion: Thyroid function indicators are associated with MAFLD. This association may potentially be mediated by ALT, HDL_C, and BMI and appears to vary depending on iodine nutritional status, though this modifying effect warrants further validation.
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