Evidence map›Paper›PMID 42327324›Full record

ArticlebioRxiv : the preprint server for biology2026

Perturbing glycosylphosphatidylinositol (GPI)-anchor biosynthesis alters cell wall architecture and modulates fungal morphology.

Hui Ting Chu, Isha Gautam, Surya Pavan Yenamandra, Tuo Wang, Prakash Arumugam

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hui Ting ChuSingapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science, Technology and Research (A*STAR), 31 Biopolis Way, Nanos, Singapore 138669, Singapore.
Isha GautamDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Surya Pavan YenamandraEnvironmental Health Institute, 11 Biopolis Way, Singapore 138667, Singapore.
Tuo WangDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-1801-924X
Prakash ArumugamSingapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science, Technology and Research (A*STAR), 31 Biopolis Way, Nanos, Singapore 138669, Singapore.

Funding

Revealing the Cell Wall Organization of Fungal Pathogens and Structural Responses to Antifungal Drugs Using Cellular Solid-State NMRR01AI173270 · NIAID · MICHIGAN STATE UNIVERSITY · PI Tuo Wang · 2023 to 2026
$1.5M
NIAID NIH HHS R01 AI173270
6 · The paper itself

Abstract

Filamentous fungi are widely used for industrial protein production but their tendency to form dense mycelial pellets limits nutrient transfer, oxygen uptake and fermentation efficiency. While cell wall components are known to influence fungal aggregation, the molecular mechanisms linking cell wall biosynthesis to macroscopic morphology remain poorly defined. Using

Identifiers

PMID42327324
PMCPMC13278039

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.