Evidence map›Paper›PMID 42327304›Full record

ArticlebioRxiv : the preprint server for biology2026

Isolation of postnatal human neural stem cells.

Daniel Dan Liu, Anna E Eastman, Nicole L Womack-Gambrel, Chang N Kim, Joy Q He, Suyash Raj, Emily Reilly, Rahul Sinha, Nobuko Uchida, Kelly Chau and 14 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Daniel Dan LiuInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0003-0100-5973
Anna E EastmanInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-1455-291X
Nicole L Womack-GambrelInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Chang N KimWeill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.
Joy Q HeInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Suyash RajInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Emily ReillyInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Rahul SinhaInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Nobuko UchidaInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Kelly ChauDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Benjamin F Ohene-GambillInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Samrat ThapaInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Emon NasajpourDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Julia A BelkInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Norma F NeffChan Zuckerberg Biohub, Stanford, CA, USA.
Siddhartha JaiswalInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
H Westley PhillipsDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Meagan ChambersDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Claudia K PetritschDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Gerald A GrantDepartment of Neurosurgery, Duke University School of Medicine, Durham, NC, USA.
Laura M ProloDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0001-7737-8675
Jody E HooperDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Tomasz J NowakowskiWeill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-2345-4964
Irving L WeissmanInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007365 · NIGMS · STANFORD UNIVERSITY · PI CHUA, KATRIN F · 1985 to 2021
$33.8M
Medical Scientist Training ProgramT32GM145402 · NIGMS · STANFORD UNIVERSITY · PI Katrin F. Chua · 2022 to 2026
$10.0M
Stem Cell Biology, Cancer Stem Cell Biology, and Cancer ImmunotherapyR35CA220434 · NCI · STANFORD UNIVERSITY · PI WEISSMAN, IRVING L. · 2017 to 2023
$6.7M
Developmental Timing During Cortical DevelopmentR01NS123263 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Tomasz Nowakowski · 2022 to 2026
$2.1M
NexTGen - STANFORDOT2CA278686 · NCI · STANFORD UNIVERSITY · PI Carolyn Bertozzi · 2022 to 2026
$1.2M
NCI NIH HHS OT2 CA278686NCI NIH HHS R35 CA220434NIGMS NIH HHS T32 GM007365NIGMS NIH HHS T32 GM145402NINDS NIH HHS R01 NS123263
6 · The paper itself

Abstract

While it was once thought that neurogenesis is complete by birth, it is now apparent that the human brain continues to generate new neurons postnatally, at least into childhood. While much attention has been focused on postnatally-born neurons, their presumed progenitor - the postnatal neural stem cell (NSC) - remains poorly characterized. Using index sorting, we identify and prospectively isolate two subsets of NSCs from the postnatal human brain, and describe their differentiation dynamics using clonal barcoding and in vivo xenotransplantation. We demonstrate an A2B5

Indexed as

neural stem cellsneurodevelopmentpostnatal neurogenesis

Identifiers

PMID42327304
PMCPMC13278174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.