Evidence map›Paper›PMID 42327231›Full record

ArticlebioRxiv : the preprint server for biology2026

HSSM: A Widely Applicable Toolbox for Hierarchical Bayesian Neurocognitive Modeling.

Alexander Fengler, Yang Xu, Krishn Bera, Carlos Paniagua, Aisulu Omar, Michael J Frank

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander FenglerDepartment of Cognitive and Psychological Sciences, Brown University, United States.ORCID 0000-0002-0104-3905
Yang XuCenter for Computation and Visualization, Brown University, United States.
Krishn BeraDepartment of Cognitive and Psychological Sciences, Brown University, United States.ORCID 0000-0002-0356-4659
Carlos PaniaguaCenter for Computation and Visualization, Brown University, United States.
Aisulu OmarCenter for Computation and Visualization, Brown University, United States.
Michael J FrankDepartment of Cognitive and Psychological Sciences, Brown University, United States.ORCID 0000-0001-8451-0523

Funding

The neural network of OCD, linking NHP and human studiesP50MH106435 · NIMH · UNIVERSITY OF ROCHESTER · PI Suzanne N Haber · 2015 to 2026
$28.9M
Project 4_Bruchas : Circuit-level Approaches for Dissecting Approach/Avoidance Behaviors Mediated by Nociceptin Systems in MiceP50MH119467 · NIMH · MCLEAN HOSPITAL · PI FRANK, MICHAEL J. · 2020 to 2024
$15.9M
Brain Science Compute ClusterS10OD025181 · OD · BROWN UNIVERSITY · PI SANES, JEROME N · 2019 to 2019
$600k
NIH HHS S10 OD025181NIMH NIH HHS P50 MH106435NIMH NIH HHS P50 MH119467
6 · The paper itself

Abstract

Computational models are central to cognitive neuroscience, but their rigorous application to experimental datasets is often constrained to a narrow set of canonical models that afford tractable analytical computations. We introduce the HSSM (Hierarchical Sequential Sampling Model) ecosystem, a Python toolbox that democratizes access to a broad, extensible array of neurocognitive process models through hierarchical Bayesian inference. Naturally leveraging simulation-based inference via likelihood surrogates, HSSM enables fast parameter estimation for models lacking closed-form likelihoods. Built atop PyMC and Bambi, HSSM provides a user-friendly formula syntax for specifying hierarchical mixed-effects regressions on model parameters, incorporating trial-by-trial neural or physiological covariates. The ecosystem allows fast model simulation and training data generation, as well as the neural network training utilities to deploy surrogate likelihood networks via HuggingFace. Contributions are designed to benefit not only the single researcher working on a problem, but organically, the entire research community. Together, the tools in the HSSM ecosystem bridge the interests of computational theorists as well as experimentalists, accelerating the cycle from model development to rigorous empirical testing.

Identifiers

PMID42327231
PMCPMC13277915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.