Evidence map›Paper›PMID 42327185›Full record

ArticlebioRxiv : the preprint server for biology2026

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Jennell Jennett, Martin Olmos, Ka Man Lam, Sarah Midou, Nicholas V DiPatrizio, Meera G Nair

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Martin Olmos
Ka Man Lam
Sarah Midou
Nicholas V DiPatrizioORCID 0000-0001-8423-0695

Funding

RELMalpha-expressing macrophages mediate host disease tolerance in mucosal infectionR01AI153195 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI NAIR, MEERA GOH · 2020 to 2024
$3.5M
Sex-dependent innate immune mechanisms in type 2 immunity and obesityR01AI191470 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Meera Goh Nair · 2025 to 2026
$1.4M
Endocannabinoid regulation of host-helminth interactionR21AI135500 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI DIPATRIZIO, NICHOLAS VINCENT, NAIR, MEERA GOH · 2018 to 2019
$509k
Innate immune pathways underlying sexual dimorphism in obesity pathogenesisR21AI180561 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI COSS, DJURDJICA, NAIR, MEERA GOH · 2024 to 2025
$407k
NIAID NIH HHS R01 AI153195NIAID NIH HHS R01 AI191470NIAID NIH HHS R21 AI135500NIAID NIH HHS R21 AI180561
6 · The paper itself

Abstract

Cannabis use is increasing globally, yet the immunological effects of Δ9-tetrahydrocannabinol (THC), the main intoxicating component of cannabis, remain incompletely understood. Given prior evidence that endocannabinoid signaling influences helminth immunity and type 2 inflammation, we investigated how sustained THC exposure alters immune responses to the helminth Summary Sentence: THC reshapes helminth-induced type 2 inflammation by restraining inflammatory leukocyte responses and reprogramming lung eosinophils and macrophages.

Identifiers

PMID42327185
PMCPMC13278042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.