Evidence map›Paper›PMID 42327113›Full record

ArticlebioRxiv : the preprint server for biology2026

What can a neuron compute.

Ido Aizenbud, David Beniaguev, Noam Pnueli, Idan Segev, Michael London

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ido AizenbudThe Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0009-0006-6855-567X
David BeniaguevThe Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0001-6929-8640
Noam PnueliThe Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem, Israel.
Idan SegevThe Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0001-7279-9630
Michael LondonThe Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0001-5137-1707

Funding

Reexamining the Role of Dendrites in Neuronal FunctionRM1NS132981 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Jayeeta Basu, RAFAEL YUSTE · 2023 to 2026
$10.3M
NINDS NIH HHS RM1 NS132981
6 · The paper itself

Abstract

Cortical pyramidal neurons possess elaborate dendritic trees with diverse nonlinear membrane conductances and thousands of plastic synapses, suggesting substantial computational capabilities at the single-cell level. Yet, what can a neuron compute remains an open question, largely due to the lack of a systematic framework to quantify its computational capabilities. We introduce

Indexed as

compartmental modelingcortical pyramidal cellsdeep neural networksdendritic computationDendritic nonlinearityNeuroAINMDAsingle neuron computation

Identifiers

PMID42327113
PMCPMC13277905

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.