Evidence map›Paper›PMID 42327044›Full record

ArticlebioRxiv : the preprint server for biology2026

Two SID-1-dependent genes sensitive to heritable epigenetic changes can also impact reproduction.

Aishwarya Sathya, Nathan M Shugarts Devanapally, Andrew L Yi, Antony M Jose

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aishwarya SathyaDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742.ORCID 0000-0001-6128-0040
Nathan M Shugarts DevanapallyDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742.ORCID 0000-0003-4140-7010
Andrew L YiDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742.
Antony M JoseDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742.ORCID 0000-0003-1405-0618

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Transgenerational gene silencing by extracellular RNAR01GM124356 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI JOSE, ANTONY MERLIN · 2018 to 2025
$2.8M
Training Program in Cell & Molecular BiologyT32GM080201 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI DELWICHE, CHARLES F · 2009 to 2019
$1.6M
NIGMS NIH HHS R01 GM124356NIGMS NIH HHS T32 GM080201NIH HHS P40 OD010440
6 · The paper itself

Abstract

Import of double-stranded RNA (dsRNA) into the germ line can have consequences that last for many generations. However, the role of such transgenerational regulation by extracellular dsRNA is unclear. In the nematode

Indexed as

germlineRNAispermtransgenerational epigenetic inheritance

Identifiers

PMID42327044
PMCPMC13277809

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.