Evidence map›Paper›PMID 42326951›Full record

ArticleFrontiers in public health2026

Body mass index mediates the association between children's dietary inflammatory index and obstructive sleep apnea-hypopnea syndrome in children: a cross-sectional study.

Yi Wen, Jinglan Chen, Xia Yang, Shiqi Xie, Jianrong Zhou, Xiaozhu Zhang

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Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Yi WenSchool of Nursing, Chongqing Medical University, Chongqing, China.
Jinglan ChenDepartment of Eye and Otorhinolaryngology, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Xia YangSchool of Social Development and Public Policy, Fudan University, Shanghai, China.
Shiqi XieSchool of Nursing, Chongqing Medical University, Chongqing, China.
Jianrong ZhouSchool of Nursing, Chongqing Medical University, Chongqing, China.
Xiaozhu ZhangSchool of Nursing, Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Children's Dietary Inflammatory Index (C-DII) is associated with elevated body mass index (BMI), a major risk factor for pediatric obstructive sleep apnea-hypopnea syndrome (OSAHS). However, the interrelationships between pro-inflammatory diets, BMI, and OSAHS severity in children remain unclear. This study aimed to examine the association between C-DII and OSAHS severity and assess whether BMI statistically explained the association. Methods: This cross-sectional study involved 297 children diagnosed with OSAHS. Dietary intake was assessed using a 3-day 24-h dietary recall (including two weekdays and one weekend) to calculate the C-DII scores. All participants underwent polysomnography to determine the obstructive apnea-hypopnea index (OAHI) as an indicator of OSAHS severity. Multiple linear regression analyses evaluated the association between C-DII tertiles (T1 as reference compared to T2 and T3) and OAHI, adjusting for key sociodemographic and clinical covariates. A mediation analysis using the PROCESS macro quantified the proportion of the association statistically attributable to BMI. Results: After covariate adjustment, the highest C-DII tertile (T3, pro-inflammatory diet) had a significantly higher OAHI vs. the lowest tertile (T1) (β = 2.04, 95% CI: 0.07-4.01, Conclusions: A pro-inflammatory diet (higher C-DII score) is associated with more severe pediatric OSAHS. This association was largely statistically explained by BMI. Causality cannot be inferred from this cross-sectional study. These findings support integrating dietary and weight strategies in pediatric OSAHS care. Nonetheless, longitudinal studies are needed to clarify diet-specific effects beyond weight control.

Indexed as

Body Mass IndexDietInflammationSleep Apnea, ObstructiveChildCross-Sectional StudiesFemaleHumansMalePolysomnographyRisk FactorsSeverity of Illness Indexbody mass indexchildren's dietary inflammatory indexcross-sectional studymediating effectpediatric obstructive sleep apnea-hypopnea syndrome

Identifiers

PMID42326951
PMCPMC13279400

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