Evidence map›Paper›PMID 42326891›Full record

ArticleJournal of substance use2026

Impacts of personal or family COVID-19 infection on health-related quality of life among patients with opioid use disorder.

Zoe M Weinstein, Kara M Magane, Sara Lodi, Margaret Shea, Clara A Chen, Delilah Doeleman, Emily Oot, Angela R Bazzi, Melissa Davoust, Alicia S Ventura and 2 more

Abstract read
In one paragraph

Article in Journal of substance use, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zoe M WeinsteinClinical Addiction Research & Education (CARE) Unit, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts.ORCID 0000-0002-8116-6023
Kara M MaganeDepartment of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts.
Sara LodiDepartment of Biostatistics, Boston University School of Public Health, Boston, MA.
Margaret SheaBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, Massachusetts.
Clara A ChenBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, Massachusetts.
Delilah DoelemanDepartment of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts.
Emily OotDepartment of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts.
Angela R BazziDepartment of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts.
Melissa DavoustDepartment of Health Law, Policy & Management, Boston University School of Public Health, Boston, Massachusetts.
Alicia S VenturaClinical Addiction Research & Education (CARE) Unit, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts.
Samantha BlakemoreClinical Addiction Research & Education (CARE) Unit, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts.
Richard SaitzClinical Addiction Research & Education (CARE) Unit, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts.

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Preventing HIV infection among people who inject drugs during COVID-19K01DA043412 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAZZI, ANGELA ROBERTSON · 2017 to 2021
$934k
NCATS NIH HHS UL1 TR001430NIDA NIH HHS K01 DA043412
6 · The paper itself

Abstract

Objective: To assess the impacts of personal or family COVID-19 infection on health-related quality of life (HRQOL) among patients with opioid use disorder (OUD). Methods: From July 2021-July 2022, adults recruited from an OUD treatment clinic self-reported personal or family experiences of COVID-19 infection including exposures, quarantine, symptoms, positive tests, treatment, and severe illness. (one point for each positive response). HRQOL outcomes included (1) single-item general health (range: poor to excellent), and (2) HRQOL dimensions (problems with mobility, self-care, usual activities, pain/discomfort, anxiety/depression). Logistic regression quantified associations between COVID-19 impact scores and odds of (1) poorer general health and (2) each HRQOL dimension. Results: Among 149 participants, the average age was 49, 62.2% were white/non-Hispanic, 57% were male and median COVID-19 impact score was 4(IQR: 2-8). Many experienced problems with mobility (41.9%), usual activities (41.9%), and anxiety/depression (73.0%). Higher COVID-19 scores were associated with increased odds of problems with mobility, usual activities, and anxiety/depression (aOR=1.10, 95%CI:1.02-1.17; aOR=1.07 95%CI:1.00-1.14; aOR=1.21, 95%CI:1.09-1.34, respectively). Conclusions: Increased COVID-19 infection impacts were associated with specific HRQOL problems with mobility, usual activities and anxiety/depression. Resources are needed to protect HRQOL for this at-risk population during times of stress and healthcare disruption.

Indexed as

COVID-19Opioid Use DisorderQuality of Life

Identifiers

PMID42326891
PMCPMC13278480

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.