Evidence map›Paper›PMID 42326865›Full record

ArticleACS measurement science au2026

Selective Preconcentration and Mass Spectrometry Profiling of Charged Extracellular Modified Ribonucleosides by Borate Complexation and Temperature-Assisted Ionic Liquid Microextraction.

Gabriella M Floro, Colin P McCarragher, Yu-Li Shih, Kevin D Clark

Abstract read
In one paragraph

Article in ACS measurement science au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gabriella M FloroDepartment of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.ORCID https://orcid.org/0009-0009-2096-3115
Colin P McCarragherDepartment of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.ORCID https://orcid.org/0009-0008-2065-6185
Yu-Li ShihDepartment of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.
Kevin D ClarkDepartment of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.ORCID https://orcid.org/0000-0002-0576-7716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular modified ribonucleosides have recently emerged as potent cell-to-cell signaling molecules, but their low abundance in complex biofluids has impeded progress toward understanding the full complement of their functions. A major bottleneck is the lack of sample preparation techniques that can extract, purify, and preconcentrate extracellular modified nucleosides from biological fluids. Here, we address this limitation by developing a borate complexation, temperature-assisted ionic liquid microextraction (BTAIL-ME) technique. BTAIL-ME capitalizes on the formation of boronate esters with the

Indexed as

ionic liquidsmass spectrometrymicroextractionmodified ribonucleosidesRNA modifications

Identifiers

PMID42326865
PMCPMC13281200

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.