Evidence map›Paper›PMID 42326837›Full record

ArticleGut microbiome (Cambridge, England)2026

Associations between gut microbiome and 24-hour blood pressure variability: a cross-sectional study highlighting sex differences and potential therapeutic targets.

Preeti Dinesh Virwani, Gordon Qian, Carman Nga-Man Cheung, Tommy K K T S Pijarnvanit, Matthew S S Hsu, Yick Hin Chow, Lok Kan Tang, Yiu-Hei Tse, Jia-Wen Xian, Shirley Sau-Wing Lam and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbiome (Cambridge, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Preeti Dinesh VirwaniDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.ORCID https://orcid.org/0009-0000-1213-926X
Gordon QianSchool of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, China.
Carman Nga-Man CheungDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Tommy K K T S PijarnvanitDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Matthew S S HsuDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Yick Hin ChowDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Lok Kan TangDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Yiu-Hei TseDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Jia-Wen XianDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Shirley Sau-Wing LamDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Crystal P I LeeDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Chelsea C W LoDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Roxanna K C LiuDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Tsi Lok HoDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Bak Yue ChowDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Kin Sum LeungSchool of Biological Sciences, Faculty of Science, The University of Hong Kong, China.
Emily K K LoSchool of Biological Sciences, Faculty of Science, The University of Hong Kong, China.
Man-Fung YuenDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Suet Yi LeungDepartment of Pathology, LKS Faculty of Medicine, The University of Hong Kong, China.
Ivan Fan-Ngai HungDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Jimmy Chun Yu LouieSchool of Biological Sciences, Faculty of Science, The University of Hong Kong, China.
Kay-Cheong TeoDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.
Hani El-NezamiSchool of Biological Sciences, Faculty of Science, The University of Hong Kong, China.
Joshua Wing Kei HoSchool of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, China.
Kui Kai LauDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood pressure (BP) variability is an independent risk factor for cardiovascular disease. Gut microbiome (GM) regulates BP, but its association with BP variability remains unclear. We examined the association of GM, determined by stool shotgun metagenomic sequencing, with 24-hour BP average real variability (ARV) assessed by ambulatory BP monitoring in 235 community-dwelling adults from Hong Kong (111 men and 124 women, mean age 54 ± 6 years) using covariate-adjusted statistical models. The GM alpha diversity was negatively associated with systolic BP (SBP) ARV in the full cohort, driven by women. In men, beta diversity of both GM species and function was associated with SBP ARV, while

Indexed as

24-hour BP variabilitycross-sectional studygut microbiomesex differences

Identifiers

PMID42326837
PMCPMC13279954

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.