Evidence map›Paper›PMID 42326719›Full record

ArticleACS omega2026

A Validated LC-MS/MS Method for the Determination of Perospirone in Human Plasma and Its Pharmacokinetic Application in Healthy Volunteers.

Benkai Qin, Huina Zhang, Hangyu Zhao, Yuchen Su, Yifu Kong, Shengshuo Zhang, Luwei Wang, Yonghua Yu, Jie Gu, Tingting Lou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Benkai QinFuan Pharmaceutical Group Ningbo Team Pharmaceutical Co., Ltd, Ningbo 315100, China.
Huina ZhangFuan Pharmaceutical Group Ningbo Team Pharmaceutical Co., Ltd, Ningbo 315100, China.
Hangyu ZhaoFuan Pharmaceutical Group Ningbo Team Pharmaceutical Co., Ltd, Ningbo 315100, China.
Yuchen SuFuan Pharmaceutical Group Ningbo Team Pharmaceutical Co., Ltd, Ningbo 315100, China.
Yifu KongFuan Pharmaceutical Group Ningbo Team Pharmaceutical Co., Ltd, Ningbo 315100, China.
Shengshuo ZhangFuan Pharmaceutical Group Ningbo Team Pharmaceutical Co., Ltd, Ningbo 315100, China.
Luwei WangTongde Hospital of Zhejiang Province, Hangzhou 310012, China.
Yonghua YuFuan Pharmaceutical Group Ningbo Team Pharmaceutical Co., Ltd, Ningbo 315100, China.ORCID https://orcid.org/0000-0001-5594-4226
Jie GuDepartment of Urology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.
Tingting LouTongde Hospital of Zhejiang Province, Hangzhou 310012, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perospirone hydrochloride hydrate is an atypical antipsychotic widely used in the management of schizophrenia. Reliable quantification of its plasma concentrations remains essential for pharmacokinetic characterization and dose optimization. A rapid, specific, and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and fully validated for the quantification of perospirone in human EDTA-K

Identifiers

PMID42326719
PMCPMC13280890

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.