Evidence map›Paper›PMID 42326578›Full record

ReviewArchives of rehabilitation research and clinical translation2026

Effectiveness of Rehabilitation Interventions on Participation in Children and Adolescents With Unilateral Cerebral Palsy: A Systematic Review and Meta-Analysis.

María Coello-Villalón, Purificación López-Muñoz, Giuseppina Sgandurra, Cristina Lirio-Romero, Ana Torres-Costoso, Rocío Palomo-Carrión

Abstract readReview
In one paragraph

Review in Archives of rehabilitation research and clinical translation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

María Coello-VillalónResearch Group of Pediatric and Neurologic Physiotherapy, ImproveLab, Universidad de Castilla-La Mancha, Toledo, Spain.
Purificación López-MuñozResearch Group of Pediatric and Neurologic Physiotherapy, ImproveLab, Universidad de Castilla-La Mancha, Toledo, Spain.
Giuseppina SgandurraDevelopmental Neurology and Neurorehabilitation Unit, IRCCS Stella Maris Foundation, Pisa, Italy.
Cristina Lirio-RomeroResearch Group of Pediatric and Neurologic Physiotherapy, ImproveLab, Universidad de Castilla-La Mancha, Toledo, Spain.
Ana Torres-CostosoFaculty of Physiotherapy and Nursing, Department of Nursing, Physiotherapy and Occupational Therapy, University of Castilla-La Mancha, Toledo, Spain.
Rocío Palomo-CarriónResearch Group of Pediatric and Neurologic Physiotherapy, ImproveLab, Universidad de Castilla-La Mancha, Toledo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine the effectiveness of rehabilitation interventions on participation outcomes in daily living, leisure, social, and educational contexts for children and adolescents with unilateral cerebral palsy (UCP), and to identify whether specific intervention categories yield superior participation improvements. Data Sources: MEDLINE via PubMed, Physiotherapy Evidence Database, Cochrane Library, CINAHL, and Scopus were searched from inception to July 31, 2025, for randomized controlled trials (RCTs), non-RCTs, and single-arm pre-post studies involving participants aged 18 months to 18 years with UCP, rehabilitation interventions, and standardized participation measures. Study Selection: After screening 417 records, 23 studies (19 RCTs and 4 pre-post designs; total N=840) met inclusion criteria. Data Extraction: Two independent reviewers extracted study characteristics and participation outcomes. Risk of bias was assessed via Risk of Bias 2.0 and Risk Of Bias In Nonrandomized Studies of Interventions-I; certainty of evidence was judged using Grading of Recommendations Assessment, Development and Evaluation. Data Synthesis: Pooled pre-post analyses using a random-effects model (Restricted Maximum Likelihood) showed a standardized mean difference of 1.44 (95% CI: 0.95-1.92), indicating strong within-group participation improvements; however, certainty of evidence was low because of methodological limitations and high heterogeneity (I Conclusions: Rehabilitation interventions yield substantial pre-post participation gains in children and adolescents with UCP; no specific modality showed clear superiority. Intervention characteristics may be key drivers. Future RCTs with active comparators and standardized, participation-focused protocols are needed.

Indexed as

AdolescentsChildrenParticipationRehabilitationUnilateral cerebral palsy

Identifiers

PMID42326578
PMCPMC13282821

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.