Evidence map›Paper›PMID 42326523›Full record

ArticleResearch square2026

Connexin 43 Loss in Endothelial Progenitors Facilitates Functional Airway Adaptation After Lung Injury.

Maggie Dawon, Hannah F Thorndyke, Julia M Hollaway, Preeyam Patel, Bradley W Richmond, Carlyne D Cool, Edward P Manning, Jonathan A Kropski, Moumita Ghosh, Aleksandra Tata and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maggie DawonNational Jewish Health.
Hannah F ThorndykeNational Jewish Health.
Julia M HollawayNational Jewish Health.
Preeyam PatelIndependent Researcher.
Bradley W RichmondVanderbilt University Medical Center.
Carlyne D CoolNational Jewish Health.
Edward P ManningYale University.
Jonathan A KropskiVanderbilt University Medical Center.
Moumita GhoshUniversity of Colorado Anschutz Medical Campus.
Aleksandra TataDuke Medical Center.
Patrick GeraghtySUNY Downstate Medical Center.
Susan M MajkaNational Jewish Health.

Funding

Mesenchymal Vascular Progenitor Depletion Promotes Lung Aging and Susceptibility to EmphysemaR35HL161238 · NHLBI · NATIONAL JEWISH HEALTH · PI SUSAN M MAJKA · 2022 to 2026
$4.9M
Loss of progenitor function accelerates lung agingR01AG073317 · NIA · NATIONAL JEWISH HEALTH · PI SUSAN M MAJKA, Richard Lee Reinhardt · 2023 to 2026
$2.7M
Loss of progenitor function accelerates lung agingR56AG073317 · NIA · NATIONAL JEWISH HEALTH · PI MAJKA, SUSAN M, REINHARDT, RICHARD LEE · 2021 to 2021
$336k
NHLBI NIH HHS R35 HL161238NIA NIH HHS R01 AG073317NIA NIH HHS R56 AG073317
6 · The paper itself

Abstract

Connexin 43 mediated gap junction signaling between ABCG2

Indexed as

alveolar-capillary networkATP Binding Cassette Subfamily G Member 2 (Abcg2)Connexin 43 (Gja1)emphysematous loss of structurefibrosismicrovascular endothelial cellsMicrovascular endothelial progenitor cell (mvEPC)microvascular nichereparative angiogenesis

Identifiers

PMID42326523
PMCPMC13278293

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.