Evidence map›Paper›PMID 42326460›Full record

ArticleACG case reports journal2026

Nirmatrelvir-Ritonavir-Induced Pancreatitis: A Concern in the COVID Era.

Jake DeBroff, Joseph Abraham, Bo Hyung Yoon, Ian Cohen

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jake DeBroffDepartment of Internal Medicine, Mount Sinai West-Morningside, New York, NY.
Joseph AbrahamDepartment of Internal Medicine, Mount Sinai West-Morningside, New York, NY.
Bo Hyung YoonDepartment of Gastroenterology, Mount Sinai Hospital, New York, NY.
Ian CohenDepartment of Gastroenterology, Mount Sinai Hospital, New York, NY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization reports that more than 500 drugs can cause drug-induced pancreatitis. Nirmatrelvir-ritonavir (Paxlovid; Pfizer, Mission, KS) has been approved to prevent hospitalization and mortality among patients with COVID-19. A 71-year-old man presented with epigastric abdominal pain and weight loss after recently completing a 5-day course of nirmatrelvir-ritonavir. He was found to have acute pancreatitis which resolved with symptomatic treatment. Nirmatrelvir-ritonavir is a commonly used medication for the treatment of COVID-19. Ritonavir has been identified as 1 potential drug, which can cause pancreatitis. Our case report raises the awareness of the rare complication of pancreatitis from nirmatrelvir-ritonavir.

Indexed as

drug induced pancreatitisnirmatrelvir-ritonavirPaxlovid

Identifiers

PMID42326460
PMCPMC13282096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.