Evidence map›Paper›PMID 42326455›Full record

ArticleACG case reports journal2026

Undifferentiated Carcinoma With Osteoclast-like Giant Cells of the Pancreas Diagnosed by EUS-Guided Fine-Needle Biopsy.

Michele Francesco Chiappetta, Marco Murgiano, Federica Borrelli de Andreis, Cristina Ciuffini, Luigi Giovanni Papparella, Salvatore Francesco Vadalà di Prampero, Marcello Fiorani, Guido Costamagna, Milutin Bulajic

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michele Francesco ChiappettaDigestive Endoscopy Unit, Ospedale Isola Tiberina, Rome, Italy.
Marco MurgianoCatholic University of Sacred Heart, Rome, Italy.
Federica Borrelli de AndreisDigestive Endoscopy Unit, Ospedale Isola Tiberina, Rome, Italy.
Cristina CiuffiniDigestive Endoscopy Unit, Ospedale Isola Tiberina, Rome, Italy.
Luigi Giovanni PapparellaDigestive Endoscopy Unit, Ospedale Isola Tiberina, Rome, Italy.
Salvatore Francesco Vadalà di PramperoDigestive Endoscopy Unit, Ospedale Isola Tiberina, Rome, Italy.
Marcello FioraniDigestive Endoscopy Unit, Ospedale Isola Tiberina, Rome, Italy.
Guido CostamagnaDigestive Endoscopy Unit, Ospedale Isola Tiberina, Rome, Italy.
Milutin BulajicDigestive Endoscopy Unit, Ospedale Isola Tiberina, Rome, Italy.ORCID https://orcid.org/0000-0001-6106-6327

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas is an extremely rare malignancy with nonspecific radiological features, often requiring histological confirmation. We report the case of a 57-year-old woman presenting with abdominal pain and cholestasis, in whom imaging revealed a pancreatic head mass. After an initial nondiagnostic endoscopic ultrasound sampling, endoscopic ultrasound-guided fine-needle biopsy performed at our tertiary referral center allowed definitive diagnosis by identifying characteristic osteoclast-like giant cells and undifferentiated neoplastic cells with a specific immunohistochemical profile. This case highlights the key role of endoscopic ultrasound-guided fine-needle biopsy in the preoperative diagnosis of undifferentiated carcinoma with osteoclast-like giant cells.

Indexed as

endoscopic ultrasoundfine-needle biopsyosteoclast-like giant cellspancreatic cancerundifferentiated carcinoma

Identifiers

PMID42326455
PMCPMC13282049

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.