Evidence map›Paper›PMID 42326367›Full record

ArticleFrontiers in stroke2026

Flow diverters for intracranial aneurysm embolization with coil embolization in children with ruptured aneurysm: two cases reports.

Quan Zhou, Shixin Jiang, Bingbing Wang, Feng Guo

Abstract readCase Reports
In one paragraph

Article in Frontiers in stroke, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Quan ZhouShandong Second Medical University, Weifang, China.
Shixin JiangShandong Second Medical University, Weifang, China.
Bingbing WangLinyi People's Hospital Affiliated to Shandong Second Medical University, Linyi, China.
Feng GuoShandong Second Medical University, Weifang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric intracranial aneurysms are relatively rare and exhibit distinct characteristics compared with those in adults, particularly in terms of sex distribution, incidence, anatomical location, morphology, and underlying etiology. Notably, the risk of rupture and hemorrhage is substantially higher in the pediatric population. Among children younger than five years, approximately 85% of intracranial aneurysms initially present with rupture and bleeding, whereas this proportion decreases to 45% in those older than five years, still significantly exceeding the hemorrhagic risk observed in adults. Current standard treatment modalities for intracranial aneurysms include microsurgical clipping, stent-assisted coil embolization, and flow diverter implantation. However, there are relatively few reports on the use of flow diverters in pediatric patients, and the optimal antiplatelet regimen following endovascular treatment in this population remains controversial. In this study, we report two cases of ruptured giant intracranial aneurysms in children treated with flow diverter placement combined with dense coil embolization. One patient presented with a space-occupying intracerebral hematoma and subsequently developed intracranial hypertension with cerebral herniation after the procedure, necessitating decompressive craniectomy. Different antiplatelet strategies were employed in the two cases. Both patients survived and were discharged in stable condition. At 6-month follow-up, imaging demonstrated no evidence of aneurysm recurrence, and both children had a favorable quality of life.

Indexed as

case reportflow divertergiant intracranial aneurysmpediatric populationsubarachnoid hemorrhage

Identifiers

PMID42326367
PMCPMC13275361

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.