Best evidence summary of screening and management of stigma in patients with colorectal cancer and stomas.

Objective: To systematically appraise and synthesize the best available evidence on screening and management strategies for stigma among patients with colorectal cancer and stomas, providing evidence-based support for clinical practice. Methods: This study was conducted and reported in accordance with the PRISMA guidelines where applicable and the evidence summary development process proposed by the Fudan University Center for Evidence-based Nursing. Guided by the "5S" evidence pyramid model, a top-down systematic search was conducted across decision-support systems, guideline websites, professional organization websites, and major databases. The search period spanned from database inception to January 21, 2026. Multiple reviewers independently performed literature screening, critical appraisal, and evidence extraction. Results: A total of 17 publications were included, comprising two clinical decisions, six clinical practice guidelines, two expert consensuses, three evidence summaries, one systematic review, and three randomized controlled trials. The synthesized evidence generated seven thematic domains: team construction, stigma identification and assessment, educational guidance, stoma and appliance management, self-management, psychosocial support, and follow-up, yielding 32 evidence-based recommendations. Conclusion: The 32 evidence-based recommendations across seven domains provide clinically meaningful guidance for screening and managing stigma in patients with colorectal cancer and stomas. These recommendations offer an evidence-based framework for improving clinical practice. During implementation, healthcare professionals should critically appraise the applicability of evidence by considering clinical context, individual patient differences, and family and social backgrounds to optimize stigma reduction and psychosocial adaptation.