ReviewCureus2026
History, Virology, Pathogenesis, Epidemiology, and Laboratory Diagnosis of Dengue Virus: A Focused Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- External quality assurance of molecular serotype detection of dengue virus RNA among virus research and diagnostic laboratories in India.Frontiers in cellular and infection microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue virus (DENV) is a mosquito-borne flavivirus with four antigenically distinct serotypes and represents a leading cause of acute febrile illness in tropical and subtropical regions worldwide. This focused review summarizes the historical evolution of dengue disease descriptions, virus discovery, vectors and transmission dynamics, viral structure, mechanisms of pathogenesis-including antibody-dependent enhancement (ADE) and non-structural protein-1 (NS1)-mediated endothelial dysfunction-clinical classification, current epidemiology with emphasis on India, and laboratory diagnostic approaches. We highlight persistent gaps in molecular surveillance, particularly incomplete genotype and lineage characterization in routine hospital-based studies, and discuss emerging diagnostic and surveillance tools such as real-time reverse transcription polymerase chain reaction (RT-PCR), NS1 antigen detection, isothermal amplification, plaque reduction neutralization tests (PRNT), and genomic sequencing. The review concludes by outlining priorities for strengthening surveillance, diagnostics, and research to improve clinical management, vaccine policy, and public health response in endemic and peri-urban/rural settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.