Evidence map›Paper›PMID 42326232›Full record

ArticleCureus2026

The Role of Antibody Testing and Vaccination in Paediatric Recurrent Acute Otitis Media.

Karim Awad, Farah Jeffry, Bhaskar Molluru, Huw Jones, Elliot Heward

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karim AwadOtolaryngology, University of Lancashire, Preston, GBR.
Farah JeffryOtolaryngology, Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, GBR.
Bhaskar MolluruOtolaryngology, Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, GBR.
Huw JonesOtolaryngology, Betsi Cadwaladr University Health Board, St Asaph, GBR.
Elliot HewardOtolaryngology, Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecurrent acute otitis media (RAOM) is a common condition most frequently affecting children under two years of age. The main causative agent is

methodA retrospective study was performed between January and December 2023. A total of 1,004 paediatric referrals (age: ≤ 16 years) to our trust were reviewed. Patients with RAOM who underwent pneumococcal antibody testing were identified. Suboptimal antibody levels were defined as ≥ 6 low serotypes out of 13. This study took place at Royal Preston Hospital, United Kingdom.

resultsOur cohort includes 169 children with RAOM, of which 42 underwent pneumococcal antibody testing with available results. Of these patients, 19 (45.2%) had suboptimal pneumococcal antibody levels; 13 (68.4%) patients received a booster vaccine. A reduction in RAOM episodes was reported in 92.3% (12/13) of vaccinated children at follow-up (≥ 3 months), with improvement in symptoms, including otalgia, fever, and hearing loss. Adequate

conclusionThese findings indicate that approximately half of children with RAOM have suboptimal pneumococcal antibody levels, which can be successfully addressed with booster vaccination. Re-testing pneumococcal antibody levels after booster vaccination and performing

Indexed as

antibody testingbooster vaccinationotolaryngologypaediatricrecurrent acute otitis media

Identifiers

PMID42326232
PMCPMC13281995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.