Evidence map›Paper›PMID 42326071›Full record

ArticleMaterials today. Bio2026

Microviscosity-gated excited-state partitioning in a NIR-II molecular rotor for disease imaging and imaging-guided photothermal therapy.

Yufei Qin, Yaru You, Yishu Yu, Yiling Xie, Yating Sha, Jinxin Feng, Yingnan Zeng, Jiaqi Zhang, Ziyi Lei, Caicai Lu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yufei QinCenter for Advanced Materials Research & Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, PR China.
Yaru YouSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, Jiangsu, 221006, PR China.
Yishu YuSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, Jiangsu, 221006, PR China.
Yiling XieCenter for Advanced Materials Research & Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, PR China.
Yating ShaSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, Jiangsu, 221006, PR China.
Jinxin FengCenter for Advanced Materials Research & Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, PR China.
Yingnan ZengCenter for Advanced Materials Research & Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, PR China.
Jiaqi ZhangCenter for Advanced Materials Research & Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, PR China.
Ziyi LeiCenter for Advanced Materials Research & Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, PR China.
Caicai LuExperimental Teaching Platform, Beijing Normal University, Zhuhai, 519087, PR China.
Mingxi FangSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, Jiangsu, 221006, PR China.
Mengchao CuiCenter for Advanced Materials Research & Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, PR China.
Kaixiang ZhouCenter for Advanced Materials Research & Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microviscosity is an underexploited pathological cue that can be harnessed to regulate excited-state energy dissipation in organic near-infrared II (NIR-II, 1000-1700 nm) fluorophores. Here we introduce a twisted intramolecular charge transfer molecular rotor that uses microviscosity to gate radiative versus nonradiative decay, delivering a fluorescence "off" state in low-viscosity environments and a weak-but-sufficient NIR-II fluorescence turn-on in viscosity-elevated pathology while keeping nonradiative dissipation dominant for photothermal heating. A tunable donor-π-acceptor library was synthesized to drive absorption/emission toward the NIR-II window and calibrate a "dim-but-hot" photophysical profile. Molecularly dispersed

Indexed as

Acceptor engineeringLiver disease imagingMicroviscosityMolecular rotorsNear-infrared IIPhotothermal therapy

Identifiers

PMID42326071
PMCPMC13276588

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.