Evidence map›Paper›PMID 42326058›Full record

ArticleJournal of transplantation2026

Structured Multidisciplinary Care for Clinically Complex Kidney Transplant Recipients: A 12-Month Single-Center Cohort on Multidimensional Outcomes.

Beatriz Rodríguez Cubillo, Maria Ángeles Moreno de la Higuera, Aurora Viloria Jimenez, Rocío Fernández Díaz, Daniel Parra Corral, Paula Gutiérrez Sanjuan, Virginia López de la Manzanara, Diana Gimeno Álvarez, Pilar Matía, María Gemma Hernández Núñez and 8 more

Abstract read
In one paragraph

Article in Journal of transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Beatriz Rodríguez CubilloDepartment of Nephrology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.ORCID https://orcid.org/0000-0002-8272-0356
Maria Ángeles Moreno de la HigueraDepartment of Nephrology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Aurora Viloria JimenezDepartment of Palliative Care, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Rocío Fernández DíazNephrology Nursing Unit, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Daniel Parra CorralNephrology Nursing Unit, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Paula Gutiérrez SanjuanDepartment of Nephrology, Clinical Psychology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Virginia López de la ManzanaraDepartment of Nephrology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Diana Gimeno ÁlvarezDepartment of Psychiatry, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Pilar MatíaDepartment of Endocrinology and Nutrition, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
María Gemma Hernández NúñezClinical Dietetics Unit, Endocrinology and Nutrition, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
María Rosario PinoNephrology Nursing Unit, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.ORCID https://orcid.org/0000-0003-4726-2588
Miguel Archanco OlceseDepartment of Physical Medicine and Rehabilitation, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Patricia Fuente LozoyaDepartment of Nephrology, Social Work Unit, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Laura Lopez GonzalezDepartment of Microbiology and Infectious Diseases, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Natividad Calvo RomeroDepartment of Nephrology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Isabel Pérez FloresDepartment of Nephrology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Arianne Aiffil ManesesDepartment of Nephrology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.
Ana Isabel Sánchez FructosoDepartment of Nephrology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, madrid.org.

Funding

Bill & Melinda Gates Foundation INV-002022
6 · The paper itself

Abstract

Background: Kidney transplant recipients with high clinical complexity often face persistent symptom burden, emotional distress, and reduced quality of life despite stable graft function. Evidence for structured multidisciplinary programs tailored to this population remains scarce. Methods: We conducted a 12-month, single-center implementation cohort study including 73 kidney transplant recipients classified as complex using NECPAL criteria or presenting significant emotional distress. Participants were enrolled in a coordinated, person-centered multidisciplinary program integrating nephrology, psychology, palliative care, nutrition, rehabilitation, nursing, and social work. Outcomes were assessed at baseline and Months 1, 3, 6, 9, and 12 using validated instruments: ESAS-r (symptom burden), DME (emotional distress), GES (spiritual well-being), and SF-12 (health-related quality of life). Global adaptation was defined as improvement in ≥ 2 of 3 domains (symptom burden, emotional distress, and spirituality). Qualitative data from open-ended responses were thematically analyzed. Results: Over follow-up, participants showed reductions in symptom burden (ESAS-r: 35.27 to 18.60), emotional distress (DME: 12.53 to 6.57), and increases in spiritual well-being (GES: 17.21-20.12), with improvements in SF-12 general health, emotional health, and social functioning. Global adaptation was achieved by 43.9% of patients, most within 3 months. Patients with ≥ 4 NECPAL criteria exhibited the most pronounced multidimensional gains. Emotional coping emerged as the strongest predictor of improvement. Qualitative analysis revealed unreported symptoms, resilience strategies, and existential reframing. Conclusions: Implementation of a structured multidisciplinary model, combined with early complexity screening, was feasible and associated with longitudinal improvements across physical, emotional, spiritual, and functional domains in complex kidney transplant recipients. These preliminary findings suggest potential benefit-particularly for those with highest baseline vulnerability-and support the need for validation in multicenter, controlled studies.

Indexed as

kidney transplantationmultidisciplinary careNECPALquality of lifespirituality

Identifiers

PMID42326058
PMCPMC13276289

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.