Evidence map›Paper›PMID 42325963›Full record

ArticleMaterials advances2026

Biocompatible fluorescent carbon dot-based nanoprobes for G-quadruplex targeting in cancer cells.

Teodoro García-Millán, Eliza Hunt, Nina M Allen, Guilherme A Marczak Giorio, Thomas A A Oliver, Javier Ramos-Soriano, M Carmen Galan

Abstract read
In one paragraph

Article in Materials advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Teodoro García-MillánSchool of Chemistry, University of Bristol, Cantock's Close Bristol BS8 1TS UK tom.oliver@bristol.ac.uk fj.ramos@iiq.csic.es m.c.galan@bristol.ac.uk.
Eliza HuntSchool of Chemistry, University of Bristol, Cantock's Close Bristol BS8 1TS UK tom.oliver@bristol.ac.uk fj.ramos@iiq.csic.es m.c.galan@bristol.ac.uk.
Nina M AllenSchool of Chemistry, University of Bristol, Cantock's Close Bristol BS8 1TS UK tom.oliver@bristol.ac.uk fj.ramos@iiq.csic.es m.c.galan@bristol.ac.uk.ORCID https://orcid.org/0000-0002-6636-3088
Guilherme A Marczak GiorioSchool of Chemistry, University of Bristol, Cantock's Close Bristol BS8 1TS UK tom.oliver@bristol.ac.uk fj.ramos@iiq.csic.es m.c.galan@bristol.ac.uk.
Thomas A A OliverSchool of Chemistry, University of Bristol, Cantock's Close Bristol BS8 1TS UK tom.oliver@bristol.ac.uk fj.ramos@iiq.csic.es m.c.galan@bristol.ac.uk.ORCID https://orcid.org/0000-0003-3979-7857
Javier Ramos-SorianoSchool of Chemistry, University of Bristol, Cantock's Close Bristol BS8 1TS UK tom.oliver@bristol.ac.uk fj.ramos@iiq.csic.es m.c.galan@bristol.ac.uk.ORCID https://orcid.org/0000-0002-3054-0679
M Carmen GalanSchool of Chemistry, University of Bristol, Cantock's Close Bristol BS8 1TS UK tom.oliver@bristol.ac.uk fj.ramos@iiq.csic.es m.c.galan@bristol.ac.uk.ORCID https://orcid.org/0000-0001-7307-2871

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon-based nanomaterials with intrinsic luminescence properties have emerged as promising tools in biological and biomedical research; however, tuning their photoluminescence properties for bespoke applications remains challenging. Herein, we report the design and synthesis of a new class of pH-responsive, red-emissive carbon dot-based nanoprobes (average core size 2-5 nm) functionalised with a naphthalene diimide (NDI)-based G-quadruplex (G4) ligand. These hybrid nanoprobes combine the favourable chemical and optical properties of CDs with the high selectivity of classical molecular ligands for G4 DNA. The resulting NDI-CDs exhibit excitation-dependent emission with distinct maxima at ∼450, ∼490, and ∼590 nm upon excitation at 350, 460, and 520 nm, respectively, in contrast to the excitation-independent emission of the parent CDs (

Identifiers

PMID42325963
PMCPMC13277541

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.