Evidence map›Paper›PMID 42325936›Full record

ArticleCardiology research and practice2026

TAVR vs. SAVR in Patients With Severe Aortic Stenosis and Chronic Kidney Disease Undergoing Dialysis: A Comprehensive Meta-Analysis.

Maneeth Mylavarapu, Madiha Kiyani, Niharika Tanwar, Meghana Reddy, Israel Garcia, Nithin Karnan, Nidhi Laxminarayan Rao, Lakshmi Sai Meghana Kodali, Nimisha Borra

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Article in Cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maneeth MylavarapuDepartment of Cardiology, Endeavor Health Cardiovascular Institute, Endeavor Health Glenbrook Hospital, Glenview, Illinois, 60026, USA.ORCID https://orcid.org/0009-0004-2367-9615
Madiha KiyaniDepartment of Internal Medicine, MedStar Health, Georgetown University, Washington, District of Columbia, 20007, USA, georgetown.edu.
Niharika TanwarDepartment of Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, Illinois, 60657, USA, advocatehealth.com.
Meghana ReddyDepartment of Internal Medicine, Mysore Medical College & Research Institute, Mysuru, Karnataka, 570001, India, mysoremedicalcollege.com.ORCID https://orcid.org/0009-0002-1451-0581
Israel GarciaDepartment of Family Medicine, University of Southern California School of Medicine, Los Angeles, California, 90033, USA, usc.edu.ORCID https://orcid.org/0009-0009-4609-6179
Nithin KarnanDepartment of Internal Medicine, MercyOne North Iowa Medical Center, Mason City, Iowa, 50401, USA.
Nidhi Laxminarayan RaoDepartment of Internal Medicine, Adventist Health Bakersfield, Bakersfield, California, 93301, USA, adventisthealth.org.
Lakshmi Sai Meghana KodaliDepartment of Public Health & Health Sciences, University of Michigan - Flint, Flint, Michigan, 48502, USA.
Nimisha BorraDepartment of Internal Medicine, Kamineni Academy of Medical Sciences & Research Center, Hyderabad, Telangana, 500074, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with chronic kidney disease (CKD) undergoing dialysis who also suffer from severe aortic stenosis (AS) present a complex management challenge. Both transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) are treatment options, but comparative outcomes in this specific, high-risk population continue to remain unclear. Aim: This study aims to compare TAVR and SAVR postoperative clinical outcomes in patients with severe AS and CKD undergoing dialysis. Methods: According to PRISMA guidelines, a comprehensive search was conducted across various databases such as PubMed, EMBASE, Scopus, and Google Scholar. Original studies that compared the clinical outcomes between TAVR and SAVR in patients with severe AS and CKD undergoing dialysis were included in the study. Results: Ten studies, all retrospective, involving 28,625 (14,625 TAVR and 14,000 SAVR) patients with severe AS and CKD undergoing dialysis who underwent TAVR or SAVR were included in this study. Patients who underwent TAVR had significantly lower odds of in-hospital mortality (OR 0.49; 0.29, 0.84; Conclusion: In patients with severe AS and CKD undergoing dialysis, TAVR is associated with lower in-hospital mortality and shorter LOS, suggesting a favorable early safety profile and recovery in this population.

Indexed as

chronic kidney diseasedialysisend stage renal diseasemeta-analysissevere aortic stenosissurgical aortic valve replacementtranscatheter aortic valve replacement

Identifiers

PMID42325936
PMCPMC13280660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.