Evidence map›Paper›PMID 42325785›Full record

ArticleAmerican journal of translational research2026

Prediction of hospital length of stay in decompensated cirrhosis using hematologic and inflammatory indices.

Longjiao Qiao, Yanqiu Zhang, Li Xiao, Shixiu Ma, Mingyan Li, Yuebin Luo, Xinhui Xu, Ling Zhao

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Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Longjiao QiaoDepartment of Infectious Diseases, Funan County People's Hospital Northeast Intersection of Wanghua Road and Longquan Road, Lucheng Town, Funan County, Fuyang 236300, Anhui, China.
Yanqiu ZhangSchool of Pharmacy, Anhui Medical University; Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education; Institute of Clinical Pharmacology, Anhui Medical University Hefei 230032, Anhui, China.
Li XiaoDepartment of Infectious Diseases, Funan County People's Hospital Northeast Intersection of Wanghua Road and Longquan Road, Lucheng Town, Funan County, Fuyang 236300, Anhui, China.
Shixiu MaDepartment of Infectious Diseases, Funan County People's Hospital Northeast Intersection of Wanghua Road and Longquan Road, Lucheng Town, Funan County, Fuyang 236300, Anhui, China.
Mingyan LiDepartment of Infectious Diseases, Funan County People's Hospital Northeast Intersection of Wanghua Road and Longquan Road, Lucheng Town, Funan County, Fuyang 236300, Anhui, China.
Yuebin LuoDepartment of Infectious Diseases, Funan County People's Hospital Northeast Intersection of Wanghua Road and Longquan Road, Lucheng Town, Funan County, Fuyang 236300, Anhui, China.
Xinhui XuDepartment of Infectious Diseases, Funan County People's Hospital Northeast Intersection of Wanghua Road and Longquan Road, Lucheng Town, Funan County, Fuyang 236300, Anhui, China.
Ling ZhaoDepartment of Infectious Diseases, Funan County People's Hospital Northeast Intersection of Wanghua Road and Longquan Road, Lucheng Town, Funan County, Fuyang 236300, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify predictors of prolonged hospital length of stay (LOS) in decompensated cirrhosis (DC) patients and to develop a prediction model based on hematologic and inflammatory indices.

methodsWe retrospectively studied 338 hospitalized patients with DC. Admission blood indices reflecting hematologic status (hemoglobin, hematocrit, red blood cell (RBC) count, platelets, mean corpuscular volume, red cell distribution width [RDW]) and inflammation (monocyte-to-lymphocyte ratio [MLR], neutrophil-monocyte-lymphocyte ratio [NMLR], systemic inflammation response index [SIRI]) were compared between patients with LOS ≥ 7 days vs < 7 days. Multivariable logistic regression and machine learning were used to identify independent predictors of LOS ≥ 7 days, with model performance assessed by area under the receiver operating characteristic curve (AUC) on a held-out test set.

resultsOf 338 patients (median age 58 years, 33% female), 52% had LOS ≥ 7 days. Prolonged LOS was associated with more severe cytopenias (lower hemoglobin, hematocrit, RBC count, platelets) and heightened inflammation (higher RDW and inflammatory ratios; all P < 0.05). Nonlinear thresholds were observed. An admission RBC count < 5.2 × 10

conclusionsAdmission hematologic and inflammatory markers are independent predictors of prolonged LOS in DC. A machine learning model derived from routinely available low-cost tests provided moderate risk stratification for identifying patients at increased risk and supporting early clinical management.

Indexed as

Decompensated cirrhosishematologichospital lengthinflammatory

Identifiers

PMID42325785
PMCPMC13275817

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.