ArticleAmerican journal of translational research2026
Effects of dexmedetomidine on the prevention of nausea and vomiting in children after upper limb fracture surgery.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effect of dexmedetomidine on the prevention of postoperative nausea and vomiting (PONV) in children undergoing upper limb fracture surgery.
methodsA total of 82 children undergoing upper limb fracture surgery were divided into either a control group, which received general anesthesia plus brachial plexus block, or a study group, which received additional dexmedetomidine. The incidence of nausea and vomiting, postoperative agitation, perioperative hemodynamic parameters, stress-related indicators, Visual Analogue Scale (VAS) scores, and perioperative conditions were compared between the two groups.
resultsThe incidences of nausea and vomiting, postoperative agitation, and the postoperative VAS scores were significantly lower in the study group than in the control group. Compared with baseline values at T0, the levels of malondialdehyde, norepinephrine, epinephrine, and cortisol increased in both groups; however, these increases were significantly lower in the study group than in the control group. In addition, the onset time of anesthesia, awakening time, and post-anesthesia care unit (PACU) stay were all shorter in the study group than in the control group.
conclusionsThe use of dexmedetomidine in children undergoing upper limb fracture surgery can attenuate perioperative hemodynamic fluctuations and stress reactions, alleviate postoperative pain, shorten awakening time, and reduce the incidence of postoperative nausea and vomiting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.